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Browsing by Author "Mustafov, Denis"
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Analysis of SIGLEC12 expression, IMMUNOMODULATION and prognostic value in RENAL cancer using multiomic databases
Ogbodo, Amobichukwu K.; Mustafov, Denis; Arora, Mohit; Lambrou, George I.; Braoudaki, Maria; Siddiqui, Shoib (2024-01-30)Siglecs belong to a family of immune regulatory receptors predominantly found on hematopoietic cells. They interact with Sia, resulting in the activation or inhibition of the immune response. Previous reports have suggested ... -
Chemokines and chemokine receptors in colorectal cancer; multifarious roles and clinical impact
Braoudaki, Maria; Ahmad, Mohammed Saqif; Mustafov, Denis; Seriah, Sara; Siddiqui, Mohammad Naseem; Siddiqui, Shoib (2022-10-13)Colorectal cancer (CRC) is considered the second cause of cancer death worldwide. The early diagnosis plays a key role in patient prognosis and subsequently overall survival. Similar to several types of cancer, colorectal ... -
Deciphering the Role of microRNA Mediated Regulation of Coronin 1C in Glioblastoma Development and Metastasis
Mustafov, Denis; Karteris, Emmanouil; Braoudaki, Maria (2023-01-04)Glioblastoma multiforme (GBM) is a highly heterogenic and malignant brain tumour with a median survival of 15 months. The initial identification of primary glioblastomas is often challenging. Coronin 1C (CORO1C) is a key ... -
In Silico and In Vitro Mapping of Receptor-Type Protein Tyrosine Phosphatase Receptor Type D in Health and Disease: Implications for Asprosin Signalling in Endometrial Cancer and Neuroblastoma
Orton, Sophie; Karkia, Rebecca; Mustafov, Denis; Gharanei, Seley; Braoudaki, Maria; Filipe, Alice; Panfilov, Suzana; Saravi, Sayeh; Khan, Nabeel; Kyrou, Ioannis; Karteris, Emmanouil; Chatterjee, Jayanta; Randeva, Harpal S. (2024-01-30)Background: Protein Tyrosine Phosphatase Receptor Type D (PTPRD) is involved in the regulation of cell growth, differentiation, and oncogenic transformation, as well as in brain development. PTPRD also mediates the effects ... -
MicroRNA-Dependent Mechanisms Underlying the Function of a β-Amino Carbonyl Compound in Glioblastoma Cells
Mustafov, Denis; Siddiqui, Shoib; Kukol, Andreas; Lambrou, George; Waseem, Shagufta; Ahmad, Irshad; Braoudaki, Maria (2024-07-23)Glioblastoma (GB) is an aggressive brain malignancy characterized by its invasive nature. Current treatment has limited effectiveness, resulting in poor patients’ prognoses. β-Amino carbonyl (β-AC) compounds have gained ...