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Browsing by Author "Navarese, Eliano P"
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Cardiac mortality in patients randomised to elective coronary revascularisation plus medical therapy or medical therapy alone: A systematic review and meta-analysis
Navarese, Eliano P; Lansky, Alexandra; Kereiakes, Dean; Kubica, Jacek; Gurbel, Paul A; Gorog, Diana; Valgimigli, Marco; Curzen, Nick; Kandzari, David. E.; Bonaca, Marc; Brouwer, Marc; Umińska, Julia M; Jaguszewski, Milosz; Raggi, Paolo; Waksman, Ron; Leon, Martin B.; Wijns, William; Andreotti, Felicita (2021-05-18)Aims:The value of elective coronary revascularisation plus medical therapy over medical therapy alone in managing stable patients with coronary artery disease is debated. We reviewed all trials comparing the two strategies ... -
Comparison of bioavailability and antiplatelet action of ticagrelor in patients with ST-elevation myocardial infarction and non-ST-elevation myocardial infarction : A prospective, observational, single-centre study
Adamski, Piotr; Sikora, Joanna; Laskowska, Ewa; Buszko, Katarzyna; Ostrowska, Małgorzata; Umińska, Julia M; Sikora, Adam; Skibińska, Natalia; Sobczak, Przemysław; Adamska, Urszula; Rość, Danuta; Kubica, Aldona; Paciorek, Przemysław; Marszałł, Michał P; Navarese, Eliano P; Gorog, Diana A; Kubica, Jacek (2017-10-12)BACKGROUND: Data from available studies suggest that the presence of ST-elevation myocardial infarction (STEMI) may be associated with delayed and attenuated ticagrelor bioavailability and effect compared with non-ST-elevation ... -
Comparison of De-escalation of DAPT Intensity or Duration in East Asian and Western Patients with ACS Undergoing PCI: A Systematic Review and Meta-analysis
Gorog, Diana; Jeyalan, Visvesh; Markides, Rafaella I. L.; Navarese, Eliano P; Jeong, Young-Hoon; Farag, Mohamed (2023-04-18)Background Guideline-recommended dual antiplatelet therapy (DAPT; aspirin plus prasugrel/ticagrelor) for 12 months in acute coronary syndrome (ACS) patients increases bleeding, with East Asians (EAs) exhibiting higher ... -
De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an international expert panel on coronary thrombosis.
Gorog, Diana; Ferreiro, Jose Luis; Ahrens, Ingo; Ako, Junya; Geisler, Tobias; Halvorsen, Sigrun; Huber, Kurt; Jeong, Young-Hoon; Navarese, Eliano P; Rubboli, Andrea; Sibbing, Dirk; Siller-Matula, Jolanta M; Storey, Robert F.; Tan, Jack W C; Berg, Jurrien M.ten; Valgimigli, Marco; Vandenbriele, Christophe; Lip, Gregory Y H (2023-07-20)Conventional dual antiplatelet therapy (DAPT) for patients with acute coronary syndromes undergoing percutaneous coronary intervention comprises aspirin with a potent P2Y purinoceptor 12 (P2Y12) inhibitor (prasugrel or ... -
Endogenous fibrinolysis - relevance to clinical thrombosis risk assessment
Kanji, Rahim; Kubica, Jacek; Navarese, Eliano P; Gorog, Diana (2020-12-09)The development of an obstructive luminal thrombus is pathological and considered a failure of endogenous fibrinolysis. The consequences may be fatal, or result in lasting downstream organ damage. Therefore, assessment of ... -
Low-Dose Aspirin for Primary Prevention of Cardiovascular Events Comparing East Asians With Westerners: A Meta-Analysis
Kim, Rock Bum; Li, Ang; Park, Ki-Soo; Kang, Yune-Sik; Kim, Jang-Rak; Navarese, Eliano P; Gorog, Diana; Tantry, Udaya S.; Gurbel, Paul A; Hwang, Jin-Yong; Kwon, Oh-Young; Jeong, Young-Hoon (2023-09-12)Background East Asians have shown different risk profiles for both thrombophilia and bleeding than Western counterparts. Objectives The authors sought to evaluate the effect of low-dose aspirin for primary prevention between ... -
Metabolism of ticagrelor in patients with acute coronary syndromes.
Adamski, Piotr; Buszko, Katarzyna; Sikora, Joanna; Niezgoda, Piotr; Barańska, Malwina; Ostrowska, Małgorzata; Paciorek, Przemysław; Navarese, Eliano P; Gorog, Diana; Kubica, Jacek (2018-09-06)Ticagrelor is a state-of-the-art antiplatelet agent used for the treatment of patients with acute coronary syndromes (ACS). Unlike remaining oral P2Y12 receptor inhibitors ticagrelor does not require metabolic activation ... -
Should we consider low LDL-cholesterol a marker of in-hospital bleeding in patients with acute coronary syndrome undergoing percutaneous coronary intervention?
Gorog, Diana; Navarese, Eliano P; Andreotti, Felicita (2021-07-29) -
When a meta-analysis equals a single large-scale trial with meaningful follow-up
Navarese, Eliano P; Kereiakes, Dean; Gorog, Diana; Lansky, Alexandra; Andreotti, Felicita (2021-10-01)This commentary refers to ‘Cardiac mortality in patients randomised to elective coronary revascularisation plus medical therapy or medical therapy alone: a systematic review and meta-analysis’, by E.P. Navarese et al. ...