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Browsing by Author "Nazir, T."
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The effects of polyvinyl alcohol on the in vitro stability and delivery of spray-dried protein particles from surfactant-free HFA 134a-based pressurised metered dose inhalers
Liao, Y. H.; Jones, Stuart A.; Nazir, T.; Martin, Gary P.; Brown, Marc (2005-11-04)The objective of the present study was to investigate the physical stability of spray-dried proteins within surfactant-free hydrofluoroalkane (HFA) pressurised metered dose inhalers (pMDIs) during prolonged storage. Two ... -
Effects of sucrose and trehalose on the preservation of the native structure of spray-dried lysozyme
Liao, Y H; Brown, Marc; Nazir, T.; Quader, A.; Martin, G P (2002)Purpose. To investigate the effects of sucrose, trehalose, sucrose/ dextran mixtures, and sucrose/ trehalose mixtures on the preservation of the native structure of spray- dried lysozyme in the solid state. Methods. The ... -
High performance liquid chromatography of a cyclosporin A formulation on a porous graphitic carbon column
Nazir, T.; Gould, L. A.; Marriott, C.; Martin, Gary P.; Brown, Marc (1997-12)A porous graphitic column (PGC) column was employed as a stationary phase at high temperature to effect the separation of cyclosporin A (CyA) and cyclosporin U (CyU). A robust assay for the former in liposomes was also ...