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Browsing by Author "Passarini, Ilaria"
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In silico structural evaluation of short cationic antimicrobial peptides
Passarini, Ilaria; Rossiter, Sharon; Malkinson, John; Zloh, Mire (2018-06-21)Cationic peptides with antimicrobial properties are ubiquitous in nature and have been studied for many years in an attempt to design novel antibiotics. However, very few molecules are used in the clinic so far, sometimes ... -
Synthesis and in silico modelling of the potential dual mechanistic activity of small cationic peptides potentiating the antibiotic novobiocin against susceptible and multi-drug resistant Escherichia coli
Passarini, Ilaria; Ernesto de Resende, Pedro; Soares, Sarah; Tahmasi, Tadeh; Stapleton, Paul; Malkinson, John; Zloh, Mire; Rossiter, Sharon (2020-11-30)Cationic antimicrobial peptides have attracted interest, both as antimicrobial agents and for their ability to increase cell permeability to potentiate other antibiotics. However, toxicity to mammalian cells and complexity ...