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Browsing by Author "Pedone, E."
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Molecular dynamics simulations of proteins with chemically modified disulfide bonds
Godwin, A.; Pedone, E.; Balan, S.; Jumnah, R.; Brocchini, S.; Choi, J.-W.; Shaunak, S.; Zloh, Mire (2007-02)Proteins that are used as therapeutic drugs act in the extracellular microenvironment. They usually have a small number of intramolecular disulfide bonds to help maintain their tertiary structure in the vascular circulation. ...