Browsing by Author "Pettorruso, Mauro"

Now showing items 1-20 of 27

    • Aberrant salience in cannabis-induced psychosis: a comparative study 

      Ricci, Valerio; Di Muzio, Ilenia; Ceci, Franca; Di Carlo, Francesco; Mancusi, Gianluca; Piro, Tommaso; Paggi, Andrea; Pettorruso, Mauro; Vellante, Federica; De Berardis, Domenico; Martinotti, Giovanni; Maina, Giuseppe (2024-01-08)
      Background: Natural Cannabis (NC) and Synthetic Cannabinoids (SCs) use can increase the risk and exacerbate the course of psychotic disorders. These could be influenced by the Aberrant Salience (AS) construct. It refers ...

    • The benzydamine experience: A systematic review of Benzydamine abuse 

      Chiappini, Stephania; Miuli, Andrea; Mosca, Alessio; Pettorruso, Mauro; Guirguis, Amira; Corkery, John Martin; Martinotti, Giovanni; di Giannantonio, Massimo; Schifano, Fabrizio (2021-01-13)
      Background: Both prescription and over-the-counter (OTC) drugs recently emerged among novel psychoactive substances (NPS) being reported as ingested for recreational purposes. Among them, benzydamine (BZY), normally ...

    • Brexpiprazole as a new approach of treatment in somatization disorder 

      Chiappini, Stefania; Mosca, Alessio; Martinotti, Giovanni; Di Carlo, Francesco; Miuli, Andrea; Dattoli, Luigi; Pettorruso, Mauro; Di Giannantonio, Massimo (2022-01-27)
      Introduction: Somatic symptom disorder (SSD) is a mental disorder that involves one or more physical symptoms (e.g. palpitations, dizziness, diarrhoea, limb weakness, pain, and pseudo neurological symptoms) accompanied by ...

    • Club Drugs and Psychiatric Sequelae: An Issue of Vulnerability and Previous Psychiatric History 

      Martinotti, Giovanni; Del Villar, Cristina Merino; Cordoba, Andrés Garcia; Tubau, Lluís Andrés; Sánchez, Ivan Castro; Di Carlo, Francesco; Chiappini, Stefania; Pettorruso, Mauro; Schifano, Fabrizio; Di Giannantonio, Massimo (2021-06-29)
      The pursuit of pleasure among clubbers and disco-goers often involves drug use. However, whether substance use may represent a relevant risk factor contributing to the development of psychiatric symptoms and of mental ...

    • Could Cariprazine Be a Possible Choice for High Functioning Autism? A Case Report 

      Miuli, Andrea; Marrangone, Carlotta; Di Marco, Ornella; Pasino, Arianna; Stigliano, Gianfranco; Mosca, Alessio; Pettorruso, Mauro; Schifano, Fabrizio; Martinotti, Giovanni (2023-12-01)
      This case report was conducted by searching for the following keywords on PubMed: High Functioning Autism, Autism Spectrum Disorder, cariprazine, aripiprazole, partial agonist antipsychotic, DRD2/DRD3. High Functioning ...

    • Duration of Untreated Disorder and Cannabis Use: An Observational Study on a Cohort of Young Italian Patients Experiencing Psychotic Experiences and Dissociative Symptoms 

      Ricci, Valerio; Martinotti, Giovanni; Ceci, Franca; Chiappini, Stefania; Di Carlo, Francesco; Burkauskas, Julius; Susini, Ottavia; Luciani, Debora; Quattrone, Diego; De Berardis, Domenico; Pettorruso, Mauro; Maina, Giuseppe; Di Giannantonio, Massimo (2021-11-30)
      Background: The Duration of Untreated Psychosis (DUP) is the time between the first-episode psychosis (FEP) and the initiation of antipsychotic treatment. It is an important predictor of several disease-related outcomes ...

    • Enhanced peripheral levels of BDNF and proBDNF: elucidating neurotrophin dynamics in cocaine use disorder 

      Pettorruso, Mauro; Miuli, Andrea; Clemente, Katia; Mancusi, Gianluca; Migliara, Giuseppe; Di Carlo, Francesco; Pernaci, Giulia; Di Crosta, Teresa; Santorelli, Mario; d’Andrea, Giacomo; De Risio, Luisa; Ciavarella, Mariaceleste; Baccolini, Valentina; Di Meo, Ilenia; Cataldo, Ivana; Sensi, Stefano L.; Martinotti, Giovanni (2024-03-01)
      Brain-derived neurotrophic factor (BDNF) and its precursor, proBDNF, are known to significantly contribute to brain homeostasis, neuroplasticity, and neuronal remodeling. Although these neurotrophins are thought to have ...

    • Focus on over-the-counter drugs’ misuse; a systematic review on antihistamines, cough medicines and decongestants 

      Schifano, Fabrizio; Chiappini, Stefania; Miuli, Andrea; Santovito, Monica Chiara; Mosca, Alessio; Santovito, Maria Chiara; Corkery, John Martin; Guirguis, Amira; Pettorruso, Mauro; di Giannantonio, Massimo; Martinotti, Giovanni (2021-05-07)
      Background: Over the past 20 years or so the drug misuse scenario has seen the emergence of both prescription-only and over-the-counter (OTC) medications being reported as ingested for recreational purposes. OTC drugs such ...

    • Focus on over-the-counter drugs’ misuse; a systematic review on antihistamines, cough medicines and decongestants 

      Schifano, Fabrizio; Chiappini, Stefania; Miuli, Andrea; Santovito, Monica Chiara; Mosca, Alessio; Santovito, Maria Chiara; Corkery, John Martin; Guirguis, Amira; Pettorruso, Mauro; di Giannantonio, Massimo; Martinotti, Giovanni (2021-05-07)
      Background: Over the past 20 years or so the drug misuse scenario has seen the emergence of both prescription-only and over-the-counter (OTC) medications being reported as ingested for recreational purposes. OTC drugs such ...

    • Focus on over-the-counter drugs’ misuse; a systematic review on antihistamines, cough medicines and decongestants 

      Schifano, Fabrizio; Chiappini, Stefania; Miuli, Andrea; Santovito, Monica Chiara; Mosca, Alessio; Santovito, Maria Chiara; Corkery, John Martin; Guirguis, Amira; Pettorruso, Mauro; di Giannantonio, Massimo; Martinotti, Giovanni (2021-05-07)
      Background: Over the past 20 years or so the drug misuse scenario has seen the emergence of both prescription-only and over-the-counter (OTC) medications being reported as ingested for recreational purposes. OTC drugs such ...

    • Gender Differences in the Psychopathology of Obesity: How Relevant Is the Role of Binge Eating Behaviors? 

      Di Natale, Chiara; Lucidi, Lorenza; Montemitro, Chiara; Pettorruso, Mauro; Collevecchio, Rebecca; Di Caprio, Lucia; Giampietro, Luana; Aceto, Liberato; Martinotti, Giovanni; Giannantonio, Massimo di (2022-07-21)
      Background: Obesity is a condition that affects humans both physically and mentally. Moreover, many psychopathological conditions can be observed in obese patients that may threaten the positive outcomes of bariatric ...

    • Ibogaine/Noribogaine in the treatment of Substance Use Disorders: a systematic review of the current literature 

      Mosca, Alessio; Chiappini, Stefania; Miuli, Andrea; Mancusi, Gianluca; Santovito, Maria Chiara; Di Carlo, Francesco; Pettorruso, Mauro; Corkery, John; Canessa, Carlos; Martinotti, Giovanni; Di Giannantonio, Massimo (2023-02-07)
      Background: Ibogaine and noribogaine are psychedelic substances with dissociative properties naturally occurring in plants of the Apocynaceae family. Research has shown their efficacy in treating substance use disorders ...

    • Investigating the effectiveness and tolerability of intranasal esketamine among older adults with treatment-resistant depression (TRD): a post-hoc analysis from the REAL-ESK study group 

      d’Andre, Giacomo; S. McIntyre, Roger; Chiappini, Stefania; Stefanelli, Giulia; Carullo, Rosalba; Andriola, Ileana; Zanardi, Raffaella; Martiadis, Vassillis; L. Sensi, Stefano; Sani, Gabriele; Clerici, Massimo; Di Lorenzo, Giorgio; Vita, Antonio; Pettorruso, Mauro; Martinotti, Giovanni (2023-07-08)
      Introduction: Treatment-resistant depression (TRD) is a serious and debilitating psychiatric disorder that frequently affects older patients. Esketamine nasal spray (ESK-NS) has recently been approved as a treatment for ...

    • Investigating the Role of Maintenance TMS Protocols for Major Depression: Systematic Review and Future Perspectives for Personalized Interventions 

      d’Andrea, Giacomo; Mancusi, Gianluca; Santovito, Maria Chiara; Marrangone, Carlotta; Martino, Fabrizio; Santorelli, Mario; Miuli, Andrea; Di Carlo, Francesco; Signorelli, Maria Salvina; Clerici, Massimo; Pettorruso, Mauro; Martinotti, Giovanni (2023-04-21)
      Repetitive Transcranial Magnetic Stimulation (rTMS) has been approved by the FDA as an effective intervention for Treatment-Resistant Depression (TRD). However, there is little evidence about maintenance protocol necessity. ...

    • Knowledge and use of over-the-counter drugs in Italy: a survey-based study in the general population 

      Chiappini, Stephania; Ceci, Franca; Mosca, Alessio; Di Carlo, Francesco; Burkauskas, Julius; Pettorruso, Mauro; Martinotti, Giovanni; Guirguis, Amira; Corkery, John Martin; Scherbaum, Norbert; Schifano, Fabrizio; di Giannantonio, Massimo (2022-10-06)
      Background: During the past decade, the misuse of over-the-counter (OTC) medicines has become a global public health concern, especially among young people. In this study, we aimed to explore the OTC consumption and related ...

    • Misuse of anticholinergic medications: a systematic review. 

      Chiappini, Stefania; Mosca, Alessio; Miuli, Andrea; Semeraro, Francesco; Mancusi, Gianluca; Santovito, Maria Chiara; Di Carlo, Francesco; Pettorruso, Mauro; Guirguis, Amira; Corkery, John M.; Martinotti, Giovanni; Schifano, Fabrizio; di Giannantonio, Massimo (2022-02-01)
      (1) Background: Over the last decade, misuse and diversion of medications has appeared to be increasingly concerning phenomena, including a range of different molecules. As current knowledge on the abuse of centrally acting ...

    • New Psychoactive Substances (NPS) and Serotonin Syndrome onset: a Systematic Review 

      Schifano, Fabrizio; Chiappini, Stephania; Corkery, John; Scherbaum, Norbert; Napoletano, Flavia; Arillotta, Davide; Catalani, Valeria; Vento, Alessandro; Pettorruso, Mauro; Martinotti, Giovanni; di Giannantonio, Massimo; Guirguis, Amira (2021-05-01)
      The use of several new psychoactive substances (NPS) has become very popular and is posing global health risks. Chemically and pharmacologically diverse molecules are constantly emerging and are presenting with a wide range ...

    • New Psychoactive Substances and suicidality: a systematic review of the current literature. 

      Chiappini, Stefania; Mosca, Alessio; Miuli, A.; Santovito, Monica Chiara; Orsolini, Laura; Corkery, John Martin; Guirguis, Amira; Pettorruso, Mauro; Martinotti, Giovanni; di Giannantonio, Massimo; Schifano, Fabrizio (2021-06-06)
      Background and Objectives: Over the past twenty years a large number of New Psychoactive Substances (NPS) has entered and modified the recreational drug scene. Their intake has been associated with health-related risks, ...

    • New trends of drug abuse in custodial settings: a systematic review on the misuse of over-the-counter drugs, prescription-only-medications, and new psychoactive substances 

      Chiappini, Stefania; Vaccaro, Giorgia; Mosca, Alessio; Miuli, Andrea; Stigliano, Gianfranco; Stefanelli, Giulia; Giovannetti, Giulia; Carullo, Rosalba; d'Andrea, Giacomo; Di Carlo, Francesco; Cavallotto, Clara; Pettorruso, Mauro; Di Petta, Gilberto; Corkery, John Martin; Guirguis, Amira; Stair, Jacqueline L.; Martinotti, Giovanni; Fazel, Seena; Schifano, Fabrizio (2024-07-30)
      The article presents a systematic literature review on the use and the psychiatric implications of over-the-counter drugs (OTC), prescription-only-medications (POM), and new psychoactive substances (NPS) within custodial ...

    • Overcoming treatment-resistant depression with machine-learning based tools: a study protocol combining EEG and clinical data to personalize glutamatergic and brain stimulation interventions (SelecTool Project) 

      Pettorruso, Mauro; Di Lorenzo, Giorgio; Benatti, Beatrice; d’Andrea, Giacomo; Cavallotto, Clara; Carullo, Rosalba; Mancusi, Gianluca; Di Marco, Ornella; Mammarella, Giovanna; D’Attilio, Antonio; Barlocci, Elisabetta; Rosa, Ilenia; Cocco, Alessio; Padula, Lorenzo Pio; Bubbico, Giovanna; Perrucci, Mauro Gianni; Guidotti, Roberto; D’Andrea, Antea; Marzetti, Laura; Zoratto, Francesca; Dell’Osso, Bernardo Maria; Martinotti, Giovanni (2024-07-17)
      Treatment-Resistant Depression (TRD) poses a substantial health and economic challenge, persisting as a major concern despite decades of extensive research into novel treatment modalities. The considerable heterogeneity ...