- UHRA Home
- Browsing by Author
Browsing by Author "Qu, Xiaozhong"
Now showing items 1-3 of 3
-
The effect of polymer architecture on the nano self-assemblies based on novel comb-shaped amphiphilic poly(allylamine)
Thompson, Colin J.; Ding, Caixia; Qu, Xiaozhong; Yang, Zhenzhong; Uchegbu, Ijeoma F.; Tetley, Laurence; Cheng, Woei Ping (2008-11)Twelve novel poly(allylamine) (PAA)-based, comb-shaped amphiphilic polymers have been developed. Hydrophobic groups of cetyl, palmitoyl and cholesteryl were randomly grafted to PAA and quaternisation was carried out on ... -
Nano self-assemblies based on cholate grafted poly-L-lysine enhanced the solubility of sterol-like drugs
Gu, Jingxia; Cheng, Woei Ping; Hoskins, Clare; Lin, Paul Kong Thoo; Zhao, Lingling; Zhu, Lijun; Qu, Xiaozhong; Yang, Zhenzhong (2011)The physicochemical compatibility between amphiphilic polymers and hydrophobic drugs has been recognized as an important issue for improving the drug solubilisation in polymeric micelle formulations. In this work, poly-L-lysine ... -
pH-triggered reversible "stealth" polycationic micelles
Gu, Jingxia; Cheng, Woei Ping; Liu, Jiguang; Lo, Sum-Yee; Smith, David; Qu, Xiaozhong; Yang, Zhenzhong (2008-01)Amphiphilic polycations with a "stealth" cationic nature have been designed and synthesized by the PEGylation of polycationic amphiphile via a novel pH responsible benzoic imine linker. The linkage is stable in aqueous ...