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Browsing by Author "Rayner, Julian C."
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Extracellular vesicles could be a putative posttranscriptional regulatory mechanism that shapes intracellular RNA levels in Plasmodium falciparum
Kioko, Mwikali; Pance, Alena; Mwangi, Shaban; Goulding, David; Kemp, Alison; Rono, Martin; Ochola-Oyier, Lynette Isabella; Bull, Pete C.; Bejon, Philip; Rayner, Julian C.; Abdi, Abdirahman I. (2023-10-13)Plasmodium falciparum secretes extracellular vesicles (PfEVs) that contain parasite-derived RNA. However, the significance of the secreted RNA remains unexplored. Here, we compare secreted and intracellular RNA from asexual ... -
Novel stem cell technologies are powerful tools to understand the impact of human factors on Plasmodium falciparum malaria
Pance, Alena; Ng, Bee Ling; Mwikali, Kioko; Koutsourakis, Manousos; Agu, Chukwuma; Rouhani, Foad J.; Montandon, Ruddy; Law, Frances; Ponstingl, Hannes; Rayner, Julian C. (2023-12-19)Plasmodium falciparum parasites have a complex life cycle, but the most clinically relevant stage of the disease is the invasion of erythrocytes and the proliferation of the parasite in the blood. The influence of human ...