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Browsing by Author "Sanchez, S."
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Chronobiological variations of indomethacin pharmacokinetic parameters in sheep
Boggio, J.C.; Valtorta, S.E.; Sanchez, S.; McKellar, Quintin (2001-08)A two-phase study to investigate the influence of administration time on pharmacokinetics of indomethacin in sheep was performed. In phase I, 12 animals were allocated to four groups, each corresponding to a different time: ... -
Dexamethasone decreases plasma levels of the prochiral fenbendazole and its chiral and achiral metabolites in sheep
Sanchez, S.; Small, J.; Jones, D.G.; McKellar, Quintin (2003-07)1. The effect of co-administration of either short- or long-acting formulations of DXM on hepatic function and the plasma pharmacokinetic behaviour of prochiral fenbendazole (FBZ) and its metabolites was evaluated in sheep. ... -
Plasma achiral and chiral pharmacokinetic behaviour of intravenous oxfendazole co-administered with piperonyl butoxide in sheep
Sanchez, S.; Jones, D.G.; Small, J.; McKellar, Quintin (2002-02)Co-administration of piperonyl butoxide (PB) potentiates fenbendazole (FBZ) in small ruminants. The resultant increase in bioavailability of FBZ and its metabolite oxfendazole (OFZ) has important implications for the ...