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Browsing by Author "Sanger, G."
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Cloning and functional expression of a human orthologue of the rat vanilloid receptor-1
Hayes, P.; Meadows, H.J.; Gunthorpe, M.J.; Harries, M.; Duckworth, M.; Cairns, W.; Harrison, D. C.; Ellington, K.; Prinjha, R.; Barton, A.; Medhurst, A.D.; Smith, G.D.; Topp, S.; Sanger, G.; Jenkins, O.; Benham, C.D.; Gloger, I.; Clarke, C. E.; Murdock, P.; Terrett, J.; Randall, A. D.; Gloger, I. S.; Davis, J. B. (2000-11-01)Capsaicin, resiniferatoxin, protons or heat have been shown to activate an ion channel, termed the rat vanilloid receptor-1 (rVR1), originally isolated by expression cloning for a capsaicin sensitive phenotype. Here we ... -
Mutation of Histidine 286 of the human P2X4 receptor leads to loss of pH sensitivity
Clarke, C.; Benham, C.D.; Bridges, A.; Sanger, G.; George, A. R.; Meadows, H.J. (2000) -
Rank-order inhibition by ω-conotoxins in human and animal autonomic nerve preparations
Sanger, G.; Ellis, E.S.; Harries, M.; Tilford, N.S.; Wardle, K.A.; Benham, C.D. (2000)The inhibitory effects of the ω-conotoxins GVIA, MVIIA and MVIIC on electrically-evoked, tetrodotoxin (10−7 M)-sensitive, autonomic nerve activity were studied using human, rat or guinea-pig vas deferens and intestinal ...