Browsing by Author "Sasmal, Aniruddha"

Now showing items 1-2 of 2

    • Evolutionary conservation of human ketodeoxynonulosonic acid production is independent of sialoglycan biosynthesis 

      Kawanishi, Kunio; Saha, Sudeshna; Diaz, Sandra; Vaill, Michael; Sasmal, Aniruddha; Siddiqui, Shoib S; Choudhury, Biswa P; Sharma, Kumar; Chen, Xi; Schoenhofen, Ian C; Sato, Chihiro; Kitajima, Ken; Freeze, Hudson H; Münster-Kühnel, Anja; Varki, Ajit (2021-03-01)
      Human metabolic incorporation of nonhuman sialic acid (Sia) N-glycolylneuraminic acid into endogenous glycans generates inflammation via preexisting antibodies, which likely contributes to red meat-induced atherosclerosis ...

    • Sialoglycan recognition is a common connection linking acidosis, zinc, and HMGB1 in sepsis 

      Siddiqui, Shoib S; Dhar, Chirag; Sundaramurthy, Venkatasubramaniam; Sasmal, Aniruddha; Yu, Hai; Bandala-Sanchez, Esther; Li, Miaomiao; Zhang, Xiaoxiao; Chen, Xi; Harrison, Leonard C; Xu, Ding; Varki, Ajit (2021-03-09)
      Blood pH is tightly maintained between 7.35 and 7.45, and acidosis (pH <7.3) indicates poor prognosis in sepsis, wherein lactic acid from anoxic tissues overwhelms the buffering capacity of blood. Poor sepsis prognosis is ...