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Advanced microscopy solutions for monitoring the kinetics and dynamics of drug-DNA targeting in living cells
Errington, Rachel J.; Ameer-Beg, S. M.; Vojnovic, B.; Patterson, Laurence H.; Zloh, Mire; Smith, P. J. (2005)Many anticancer drugs require interaction with DNA or chromatin components of tumor cells to achieve therapeutic activity. Quantification and exploration of drug targeting dynamics can be highly informative in the rational ...