Browsing by Author "Smith, Terry J."

Now showing items 1-2 of 2

    • Development of an on-disc isothermal in vitro amplification and detection of bacterial RNA 

      Brennan, Des; Coughlan, Helena; Clancy, Eoin; Dimov, Nikolay; Barry, Thomas; Kinahan, David; Ducrée, Jens; Smith, Terry J.; Galvin, Paul (2017-02-01)
      We present a centrifugal microfluidic “Lab-on-a-Disc” (LoaD) system capable of implementing nucleic acid in vitro amplification using non-contact heating and fluorescence detection. The system functionality is verified by ...

    • Solvent-selective routing for centrifugally automated solid-phase purification of RNA 

      Dimov, Nikolay; Clancy, Eoin; Gaughran, Jennifer; Boyle, David; Mc Auley, Darren; Glynn, Macdara T.; Dwyer, Róisín M.; Coughlan, Helena; Barry, Thomas; Barrett, Louise M.; Smith, Terry J.; Ducrée, Jens (2015-05-01)
      We present a disc-based module for rotationally controlled solid-phase purification of RNA from cell lysate. To this end, multi-stage routing of a sequence of aqueous and organic liquids into designated waste and elution ...