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Browsing by Author "Styliari, Ioanna D."
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Crystallographic tomography and molecular modelling of structured organic polycrystalline powders
Gajjar, Parmesh; Nguyen, Thai T. H.; Sun, Jun; Styliari, Ioanna D.; Bale, Hrishikesh; McDonald, Samuel A.; Burnett, Timothy L.; Tordoff, Benjamin; Lauridsen, Erik; Hammond, Robert B.; Murnane, Darragh; Withers, Philip J.; Roberts, Kevin J. (2021-03-02)A fundamental understanding of the behaviour of polycrystalline materials, including pharmaceuticals, is vital for control of their physicochemical and crystalline properties, which in turn has the potential to improve ... -
A digital workflow from crystallographic structure to single crystal particle attributes for predicting the formulation properties of terbutaline sulfate
Nguyen, Thai T. H.; Hammond, Robert B.; Styliari, Ioanna D.; Murnane, Darragh; Roberts, Kevin J. (2020-05-21)A detailed inter-molecular (synthonic) analysis of terbutaline sulfate, an ionic addition salt for inhalation drug formulation, is related to its crystal morphology, and through this to the surface chemistry of the habit ... -
Predicting the Strength of Cohesive and Adhesive Interparticle Interactions for Dry Powder Inhalation Blends of Terbutaline Sulfate with α‑Lactose Monohydrate
Ma, Cai Y.; Nguyen, Thai T. H.; Gajjar, Parmesh; Styliari, Ioanna D.; Hammond, Robert B.; Withers, Philip J.; Murnane, Darragh; Roberts, Kevin J. (2023-09-08)Grid-based systematic search methods are used to investigate molecule–molecule, molecule–surface, and surface–surface contributions to interparticle interactions in order to identify the crystal faces that most strongly ... -
Starch/Poly(glycerol-adipate) Nanocomposites: A Novel Oral Drug Delivery Device
Vestri, Ambra; Pearce, Amanda K.; Cavanagh, Robert; Styliari, Ioanna D.; Sanders, Carlos; Couturaud, Benoit; Schenone, Silvia; Taresco, Vincenzo; Jakobsen, Rasmus R.; Howdle, Steven M.; Musumeci, Francesca; Sagnelli, Domenico (2020-02-01)Biocompatible and bio-based materials are an appealing resource for the pharmaceutical industry. Poly(glycerol-adipate) (PGA) is a biocompatible and biodegradable polymer that can be used to produce self-assembled nanoparticles ...