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Browsing by Author "Sule, Akeem"
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Action-Outcome Knowledge Dissociates From Behavior in Obsessive-Compulsive Disorder Following Contingency Degradation
Vaghi, Matilde M; Cardinal, Rudolf N; Apergis-Schoute, Annemieke M; Fineberg, Naomi A; Sule, Akeem; Robbins, Trevor W (2019-02-01)BACKGROUND: In obsessive-compulsive disorder (OCD), actions persist despite being inappropriate to the situation and without relationship to the overall goal. Dysfunctional beliefs have traditionally been postulated to ... -
Compulsivity Reveals a Novel Dissociation between Action and Confidence
Vaghi, Matilde M.; Luyckx, Fabrice; Sule, Akeem; Fineberg, Naomi A.; Robbins, Trevor W.; De Martino, Benedetto (2017-10-11)Confidence and actions are normally tightly interwoven—if I am sure that it is going to rain, I will take an umbrella—therefore, it is difficult to understand their interplay. Stimulated by the ego-dystonic nature of ... -
Specific Frontostriatal Circuits for Impaired Cognitive Flexibility and Goal-Directed Planning in Obsessive-Compulsive Disorder : Evidence From Resting-State Functional Connectivity
Vaghi, Matilde M.; Vértes, Petra E.; Kitzbichler, Manfred G.; Apergis-Schoute, Annemieke M.; van der Flier, Febe E.; Fineberg, Naomi; Sule, Akeem; Zaman, Rashid; Voon, Valerie; Kundu, Prantik; Bullmore, Edward T.; Robbins, Trevor W. (2017-04-15)Background A recent hypothesis has suggested that core deficits in goal-directed behavior in obsessive-compulsive disorder (OCD) are caused by impaired frontostriatal function. We tested this hypothesis in OCD patients and ...