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Adherence to prophylaxis in adolescents and young adults with severe haemophilia: A quantitative study with patients
Van Os, Sandra; Troop, Nicholas; Sullivan, Keith; Hart, Daniel (2017-01-19)Introduction: haemophilia is an inherited bleeding disorder caused by a deficiency in one of the blood coagulation factors. For people affected by severe haemophilia, the deficiency can cause spontaneous internal bleeding. ... -
Changes to Physical Activity, Sitting Time, Eating Behaviours and Barriers to Exercise during the First COVID-19 ‘Lockdown’ in an English Cohort
Kass, Lindsy; Desai, Terun; Sullivan, Keith; Muniz, Daniel; Wells, Amy (2021-09-24)This study aimed to determine the effect of the first English national COVID-19 lockdown on physical activity (PA), sitting time, eating behaviours and body mass in an adult cohort. This was further examined to determine ... -
A Comparison of the Epidemiological Characteristics Between Influenza and COVID-19 Patients: A Retrospective, Observational Cohort Study.
Naji, Omar; Darwish, Iman; Bessame, Khaoula; Vaghela, Tejal; Hawkins, Anja; Elsakka, Mohamed; Merai, Hema; Lowe, Jeremy; Schechter, Miriam; Moses, Samuel; Busby, Amanda; Sullivan, Keith; Wellsted, David; Zamir, Muhammad; Kandil, Hala (2023-11-23)Background and objective It is crucial to make early differentiation between coronavirus disease 2019 (COVID-19) and seasonal influenza infections at the time of a patient's presentation to the emergency department (ED). ... -
Effect of Transdermal Magnesium Cream on Serum and Urinary Magnesium Levels in Humans: A Pilot Study
Kass, Lindsy; Rosanoff, Andrea; Tanner, Amy; McAuley, William; Sullivan, Keith; Plesset, Michael (2017-04-12)Background Oral magnesium supplementation is commonly used to support a low magnesium diet. This investigation set out to determine whether magnesium in a cream could be absorbed transdermally in humans to improve magnesium ... -
The emergence of Exercise Addiction, Body Dysmorphic Disorder, and other image-related psychopathological correlates in fitness settings : A cross sectional study
Corazza, Ornella; Simonato, Pierluigi; Demetrovics, Zsolt; Mooney, Roisin; van de Ven, Katinka; Roman-Urrestarazu, Andres; Rácmolnár, Lili; De Luca, Ilaria; Cinosi, Eduardo; Santacroce, Rita; Marini, Massimo; Wellsted, David; Sullivan, Keith; Bersani, Giuseppe; Martinotti, Giovanni (2019-04-03)INTRODUCTION: In a society that perpetuates the strive for a perfect appearance, a fit body has become synonymous with success, but simultaneously hard to achieve. This represents a fertile ground for the development of ... -
Impaired endogenous fibrinolysis in ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention is a predictor of recurrent cardiovascular events : the RISK PPCI study
Farag, Mohamed; Spinthakis, Nikolaos; Gue, Ying X.; Srinivasan, Manivannan; Sullivan, Keith; Wellsted, David; Gorog, Diana A. (2019-01-14)Aims: The endogenous fibrinolytic system serves to prevent lasting thrombotic occlusion and infarction following initiation of coronary thrombosis. We aimed to determine whether impaired endogenous fibrinolysis can identify ... -
Impaired thrombolytic status predicts adverse cardiac events in patients undergoing primary percutaneous coronary intervention
Christopoulos, Christos; Farag, Mohamed; Sullivan, Keith; Wellsted, David; Gorog, Diana A (2017-03-01)Antithrombotic medications reduce thrombosis but increase bleeding. Identification of ST-elevation myocardial infarction (STEMI) patients at risk of recurrent thrombosis could allow targeted treatment with potent antithrombotic ... -
Is incident rheumatoid arthritis interstitial lung disease associated with methotrexate treatment? Results from a multivariate analysis in the ERAS and ERAN inception cohorts
Kiely, Patrick; Busby, Amanda; Nikiphorou, Elena; Sullivan, Keith; Walsh, David; Creamer, Paul; Dixey, Josh; Young, Keith (2019-05-05)Objectives To assess predictive factors for rheumatoid arthritis interstitial lung disease (RA-ILD) in two early RA inception cohorts with a focus on methotrexate (MTX) exposure. Design Multicenter prospective early RA ... -
Low dietary magnesium intake and hypertension
Kass, Lindsy; Sullivan, Keith (2016-12-07)Abstract Purpose: Magnesium (Mg) is a key factor in blood pressure regulation. However, only in recent years, magnesium dietary intake has been studied in relation to hypertension, with equivocal conclusions. Further no ... -
Morphine Analgesia Pre-PPCI Is Associated with Prothrombotic State, Reduced Spontaneous Reperfusion and Greater Infarct Size
Farag, Mohamed; Spinthakis, Nikolaos; Srinivasan, Manivannan; Sullivan, Keith; Wellsted, David; Gorog, Diana A (2018-03-01)The emergency management of ST-elevation myocardial infarction (STEMI) involves treatment with dual-antiplatelet therapy (DAPT) and primary percutaneous coronary intervention (PPCI). Pain is generally treated with opiates, ... -
Observing Longitudinal Physical Activity and Sitting Patterns Throughout COVID-19 Restrictions Amongst UK Adults
Desai, Terun; Sullivan, Keith; Phillips, Alison; Newby, Katie; Bottoms, Lindsay (2023-06-02)Purpose: The COVID-19 global pandemic presented an insight into observing the changes in physical activity (PA) and sitting patterns of free-living adults during a unique period of intermittent enforced home confinement ... -
Physical activity and sitting time changes in response to the COVID-19 lockdown in England
Bailey, Daniel P.; Wells, Amy V.; Desai, Terun; Sullivan, Keith; Kass, Lindsy (2022-07-21)To reduce the spread of the novel coronavirus disease 2019 (COVID-19), national governments implemented measures to limit contact between citizens. This study evaluated changes in physical activity and sitting in response ... -
Relative effects of different non-vitamin K antagonist oral anticoagulants on global thrombotic status in atrial fibrillation
Farag, Mohamed; Niespialowska-Steuden, Maria; Okafor, Osita; Artman, Benjamin; Srinivasan, Manivannan; Khan, Arif; Sullivan, Keith; Wellsted, David; Gorog, Diana A (2016-10-02)Non-vitamin K antagonist oral anticoagulants (NOACs) reduce the risk of thromboembolism in patients with atrial fibrillation (AF). There has been no head-to-head comparison of the effect of these agents on ex vivo thrombotic ... -
Use of bioresorbable vascular scaffold : a meta-analysis of patients with coronary artery disease
Farag, Mohamed; Spinthakis, Nikolaos; Gorog, Diana A; Prasad, Abhiram; Sullivan, Keith; Akhtar, Zaki; Kukreja, Neville; Srinivasan, Manivannan (2016-08-26)BACKGROUND: Differences in outcomes between bioresorbable vascular scaffold (BVS) systems and drug-eluting metal stents (DES) have not been fully evaluated. We aimed to compare clinical and angiographic outcomes in randomised ...