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Browsing by Author "Szita, Nicolas"
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Electromagnetic Actuated Stiring in Microbioreactor Enabling Easier Multiplexing and Flexible Device Design
Davies, M. J.; Munro, Ian; Tan, Christabel; Tracey, M.C.; Szita, Nicolas (2014-09-07)The development of a novel electromagnetically (EM) actuated stirring method, for use in microbioreactors, is reported. Mixing in microbioreactors is critical to ensure even distribution of nutrients to microorganisms and ... -
Electromagnetic Stirring in a Microbioreactor with Non-conventional Chamber Morphology and Implementation of Multiplexed Mixing
Tan, Christabel; Davies, Matthew; McCluskey, Daniel; Munro, Ian; Nweke, Mauryn; Tracey, M.C.; Szita, Nicolas (2015-10-31)Background: Microbioreactors have recently emerged as novel tools for early bioprocess development. Mixing lies at the heart of bioreactor operation (at all scales), and the successful implementation of micro-stirring ... -
Formation and purification of tailored liposomes for drug delivery using a module-based micro continuous-flow system
Dimov, Nikolay; Kastner, Elisabeth; Hussain, Maryam; Perrie, Yvonne; Szita, Nicolas (2017-09-21)Liposomes are lipid based bilayer vesicles that can encapsulate, deliver and release low-soluble drugs and small molecules to a specific target site in the body. They are currently exploited in several nanomedicine ... -
Possible mechanisms of CO2 reduction by H2 via prebiotic vectorial electrochemistry
Vasiliadou, Rafaela; Dimov, Nikolay; Szita, Nicolas; Jordan, Sean F.; Lane, Nick (2019-10-18)Methanogens are putatively ancestral autotrophs that reduce CO 2 with H 2 to form biomass using a membrane-bound, proton-motive Fe(Ni)S protein called the energy-converting hydrogenase (Ech). At the origin of life, ... -
Simplified immobilisation method for histidine-tagged enzymes in poly(methyl methacrylate) microfluidic devices
Kulsharova, Gulsim; Dimov, Nikolay; Marques, Marco P.C.; Szita, Nicolas; Baganz, Frank (2017-12-11)Poly(methyl methacrylate) (PMMA) microfluidic devices have become promising platforms for a wide range of applications. Here we report a simple method for immobilising histidine-tagged enzymes suitable for PMMA microfluidic ...