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Synthesis and in silico modelling of the potential dual mechanistic activity of small cationic peptides potentiating the antibiotic novobiocin against susceptible and multi-drug resistant Escherichia coli
Passarini, Ilaria; Ernesto de Resende, Pedro; Soares, Sarah; Tahmasi, Tadeh; Stapleton, Paul; Malkinson, John; Zloh, Mire; Rossiter, Sharon (2020-11-30)Cationic antimicrobial peptides have attracted interest, both as antimicrobial agents and for their ability to increase cell permeability to potentiate other antibiotics. However, toxicity to mammalian cells and complexity ...