Browsing by Author "Uchegbu, I. F."

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Delivery of Peptides to the Blood and Brain after Oral Uptake of Quaternary Ammonium Palmitoyl Glycol Chitosan Nanoparticles

Lalatsa, A.; Garrett, N. L.; Ferrarelli, T.; Moger, J.; Schaetzlein, A. G.; Uchegbu, I. F. (2012-06)

The clinical development of therapeutic peptides has been restricted to peptides for non-CNS diseases and parenteral dosage forms due to the poor permeation of peptides across the gastrointestinal mucosa and the blood-brain ...
Label-free imaging of polymeric nanomedicines using coherent anti-stokes Raman scattering microscopy

Garrett, N. L.; Lalatsa, A.; Begley, D.; Mihoreanu, L.; Uchegbu, I. F.; Schaetzlein, A. G.; Moger, J. (2012-05)

Nanoparticulate drug delivery is known to greatly improve the efficacy of pharmaceuticals and has found a wide range of applications with different administration methods including oral, intravenous, transcutaneous and ...