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Ketamine supresses REM sleep and markedly increases EEG gamma oscillations in the Wistar Kyoto rat model of treatment-resistant depression
Kantor, Sandor; Lanigan, Michael; Giggins, Lauren; Lione, Lisa; Magomedova, Lilia; de Lannoy, Inés; Upton, Neil; Duxon, Mark (2023-07-09)Wistar–Kyoto (WKY) rats exhibit depression-like characteristics and decreased sensitivity to monoamine-based antidepressants, making them a suitable model of treatment-resistant depression (TRD). Ketamine has emerged ...