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Differential gene expression in cells with different p53 mutations identifies genome-wide p53 targets and shows distinct modulation of cellular pathways in response to DNA damage
Eror Barnes, Patricia; de la Concha, Maria Jose; Mwikali, Kioko; Ng, Bee Ling; Ponstingl, Hannes; Pance, Alena (BioRxiv, 2024-09-06)The fundamental transcription factor p53 regulates cellular processes and integrates signals of cellular stress, triggering a coordinated response to ensure survival of cells restored to healthy function and programmed ...