Aryldiketo acids have antibacterial activity against MDR Staphylococcus aureus strains : Structural insights based on similarity and molecular interaction fields
Author
Drakulić, B.J.
Stavri, M.
Gibbons, S.
Žižak, Ž.S.
Verbić, T.Ž.
Juranić, I.O.
Zloh, Mire
Attention
2299/10106
Abstract
(Chemical Equation Presented) Similar structure=similar activity? The effect of substituents on the antibacterial activity of aryldiketo acids has been rationalised by molecular interaction fields and similarity studies between investigated molecules and fluoroquinolone antibiotics.