Emergence of reduced susceptibility to metronidazole in Clostridium difficile
Baines, Simon D.
Fawley, Warren N
Kuijper, Ed J.
Wilcox, M. H.
Antimicrobial treatment for Clostridium difficile infection (CDI) has typically been metronidazole, although reports have questioned the efficacy of this option. We screened recently isolated C. difficile (2005-06) for susceptibility to metronidazole and compared results for historic isolates (1995-2001).