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        Emergence of reduced susceptibility to metronidazole in Clostridium difficile

        Author
        Baines, Simon D.
        O'Connor, Rachael
        Freeman, Jane
        Fawley, Warren N
        Harmanus, Celine
        Mastrantonio, Paola
        Kuijper, Ed J.
        Wilcox, M. H.
        Attention
        2299/10229
        Abstract
        Antimicrobial treatment for Clostridium difficile infection (CDI) has typically been metronidazole, although reports have questioned the efficacy of this option. We screened recently isolated C. difficile (2005-06) for susceptibility to metronidazole and compared results for historic isolates (1995-2001).
        Publication date
        2008
        Published in
        Journal of Antimicrobial Chemotherapy
        Published version
        https://doi.org/10.1093/jac/dkn313
        Other links
        http://hdl.handle.net/2299/10229
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