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dc.contributor.authorLekamwasam, S.
dc.contributor.authorTrivedi, Daksha
dc.contributor.authorKhaw, Kay Tee
dc.identifier.citationLekamwasam , S , Trivedi , D & Khaw , K T 2005 , ' An association between respiratory function and hip bone mineral density in older men: a cross-sectional study ' , Osteoporosis International , vol. 16 , no. 2 , pp. 204-7 .
dc.identifier.otherPURE: 491131
dc.identifier.otherPURE UUID: 82714488-0eeb-4f91-86d0-3d2936ddb567
dc.identifier.otherPubMed: 15197543
dc.identifier.otherScopus: 13244262777
dc.description.abstractThe association between respiratory function and bone mineral density (BMD) among women living in the community has been reported previously. We examined the association between forced expiratory volume in 1 s (FEV(1)) and BMD measured at hip using dual-energy X-ray absorptiometry in a group of 947 men (aged 65 to 76 years) recruited from general practice age-sex registers in Cambridge between 1991 and 1995. A positive and significant correlation was seen between FEV(1) and BMD measured at total hip, femoral neck, and trochanter. A unit change (1 l) in FEV(1) was associated with a change of BMD by 0.019, 0.017, and 0.026 g/cm(2) in the total hip, femoral neck, and tochanteric region, respectively. These associations were independent of possible confounding factors such as age, height, weight, smoking habit, major disease prevalence, and medications, which might affect bone metabolism. In categorical analyses, the highest BMD was seen in the highest FEV(1) quartile, while the lowest BMD was seen in the lowest FEV(1) quartile. This pattern was seen in all three skeletal sites and was independent of covariates listed above. Compared with the bottom FEV(1) quartile, mean hip BMDs in the top quartile were 2-3.5% higher. The exact mechanism of this association is not clear to us. One plausible explanation is that respiratory function and bone health both reflect common but as yet unknown determinants.en
dc.relation.ispartofOsteoporosis International
dc.subjectBody Height
dc.subjectBody Weight
dc.subjectBone Density
dc.subjectFemur Neck
dc.subjectForced Expiratory Volume
dc.titleAn association between respiratory function and hip bone mineral density in older men: a cross-sectional studyen
dc.contributor.institutionDepartment of Adult Nursing and Primary Care
dc.contributor.institutionSchool of Health and Social Work
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionCentre for Research in Public Health and Community Care
dc.contributor.institutionEvidence Based Practice
dc.contributor.institutionPatient Experience and Public Involvement
dc.contributor.institutionNursing, Midwifery and Social Work
dc.description.statusPeer reviewed
dc.relation.schoolSchool of Health and Social Work
rioxxterms.typeJournal Article/Review

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