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        Targeting glycolysis : a fragment based approach towards bifunctional inhibitors of hLDH-5

        Author
        Moorhouse, Adam D.
        Spiteri, Christian
        Sharma, Pallavi
        Zloh, Mire
        Moses, John E.
        Attention
        2299/10548
        Abstract
        hLDH-5 has emerged as a promising target for anti-glycolytic cancer chemotherapy. Here we report a first generation of bifunctional inhibitors, which show promising activity against hLDH-5.
        Publication date
        2011
        Published in
        Chemical Communications
        Published version
        https://doi.org/10.1039/c0cc01166e
        Other links
        http://hdl.handle.net/2299/10548
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