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Now showing items 61-70 of 204
Evaluation of In Vitro Bone Marrow Culture as a Tool for Assessing Mechanisms of Haematotoxicity
(2008-05-02)
Dose limiting haematotoxicity has been associated with a range of therapeutic agents used for the treatment of a number of different conditions. Haematotoxicity is usually assessed as part of the preclinical safety studies ...
The Cult Value of Quality Improvement in Healthcare: Complex Social Processes of Working With Targets
(2008-04-29)
There has been an ongoing debate on quality and what constitutes quality improvement in healthcare for several decades. Several authors identify that defining quality is an important part of that debate, yet recognise that ...
Characterisation of Nicotine Binding Sites on Human Blood Lymphocytes
(2008-04-25)
Nicotine exerts a therapeutic effect in ulcerative colitis (UC) but the mechanism underlying this effect, is not clear. However, this effect may imply that nicotine has some, as yet to be discovered, effect on the immune ...
Government, Market and Development: Brazilian Economic Development in Historical Perspective
(2008-04-09)
In the last 30 years the World has been swept by neoliberal doctrine. Under neoliberal conceptions, freedom of the market mechanism has precedence in the process of development. Neoliberalism has had a major impact on the ...
Children of the Poor in London 1700 - 1780
(2008-04-02)
Poor children are elusive in historical records, essentially invisible and unheard, and there is a significant gap in the secondary literature for the period 1700 to 1780. This thesis uses a range of largely unexplored ...
Cultural Variables Affecting Client/Therapist Consonance: the Perception of Efficacy in Arts Therapies Group Treatment
(2008-04-01)
This thesis addresses the hypothesis
“ Intragroup cultural differences between client and therapist will adversely affect client – therapist consonance in their perception of arts therapies group treatment”
The ...
Computational Modelling of the Neural Systems Involved in Schizophrenia
(2008-04-01)
The aim of this thesis is to improve our understanding of the neural systems involved in schizophrenia by suggesting possible avenues for future computational modelling in an attempt to make sense of the vast number of ...
Rural Businesses on Vancouver Island: Challenges and Opportunities
(2008-03-31)
Many rural areas are undergoing structural changes as jobs in forestry, fishing, mining, agricultural and other natural resource-based industries decline. These communities, often based around these industries, are generally ...
An Exploration of Owner-Manager Problem Solving Practices in Small Firms: The Central Vancouver Island Experience
(2008-03-31)
A significant amount of research in the field of small business management has
correlated small firm performance with the sophistication of overall management
skills (see, for example, Gasse, 1997; Gadenne, 1998; Zinger, ...
Curricular Processes as Practice: The Emergence of Excellence in a Medical School
(2008-03-28)
This thesis deals with two related questions. The first relates to a critical inquiry into the processes of curriculum creation and formation within a medical school which has undergone a significant curriculum revision. ...