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dc.contributor.authorGuo, X. X.
dc.contributor.authorCiortea, L. I.
dc.contributor.authorChilcott, Robert
dc.contributor.authorImhof, R. E.
dc.contributor.authorXiao, P.
dc.date.accessioned2013-06-19T07:45:45Z
dc.date.available2013-06-19T07:45:45Z
dc.date.issued2001
dc.identifier.citationGuo , X X , Ciortea , L I , Chilcott , R , Imhof , R E & Xiao , P 2001 , ' Opto-thermal measurement of barrier cream residence time on skin in-vivo ' , Analytical Sciences , vol. 17 , pp. S346-S348 .
dc.identifier.issn0910-6340
dc.identifier.otherPURE: 678566
dc.identifier.otherPURE UUID: c1874762-3ef8-485e-83de-d8d2424c8c83
dc.identifier.otherWOS: 000168481200099
dc.identifier.urihttp://hdl.handle.net/2299/10841
dc.description.abstractWe report the non-invasive opto-thermal measurement of the residence time of a barrier cream on in-vivo skin. These measurements revealed an approximately exponential decrease of cream layer thickness with a 1/e disappearance time of similar to 60 minutes. Measurements on a cream layer on a polymer substrate under otherwise similar conditions confirmed that penetration into the stratum corneum, rather than abrasion or evaporative loss, was the main cause of the observed disappearance.en
dc.format.extent3
dc.language.isoeng
dc.relation.ispartofAnalytical Sciences
dc.subjectCONTACT-DERMATITIS
dc.titleOpto-thermal measurement of barrier cream residence time on skin in-vivoen
dc.contributor.institutionDepartment of Pharmacy
dc.contributor.institutionPharmaceutics
dc.contributor.institutionCentre for Research into Topical Drug Delivery and Toxicology
dc.contributor.institutionToxicology
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.description.statusPeer reviewed
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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