| dc.contributor.author | Guo, X. X. | |
| dc.contributor.author | Ciortea, L. I. | |
| dc.contributor.author | Chilcott, Robert | |
| dc.contributor.author | Imhof, R. E. | |
| dc.contributor.author | Xiao, P. | |
| dc.date.accessioned | 2013-06-19T07:45:45Z | |
| dc.date.available | 2013-06-19T07:45:45Z | |
| dc.date.issued | 2001 | |
| dc.identifier.citation | Guo , X X , Ciortea , L I , Chilcott , R , Imhof , R E & Xiao , P 2001 , ' Opto-thermal measurement of barrier cream residence time on skin in-vivo ' , Analytical Sciences , vol. 17 , pp. S346-S348 . | |
| dc.identifier.issn | 0910-6340 | |
| dc.identifier.uri | http://hdl.handle.net/2299/10841 | |
| dc.description.abstract | We report the non-invasive opto-thermal measurement of the residence time of a barrier cream on in-vivo skin. These measurements revealed an approximately exponential decrease of cream layer thickness with a 1/e disappearance time of similar to 60 minutes. Measurements on a cream layer on a polymer substrate under otherwise similar conditions confirmed that penetration into the stratum corneum, rather than abrasion or evaporative loss, was the main cause of the observed disappearance. | en |
| dc.format.extent | 3 | |
| dc.language.iso | eng | |
| dc.relation.ispartof | Analytical Sciences | |
| dc.subject | CONTACT-DERMATITIS | |
| dc.title | Opto-thermal measurement of barrier cream residence time on skin in-vivo | en |
| dc.contributor.institution | Pharmaceutics | |
| dc.contributor.institution | Centre for Research into Topical Drug Delivery and Toxicology | |
| dc.contributor.institution | Toxicology | |
| dc.contributor.institution | School of Life and Medical Sciences | |
| dc.contributor.institution | Centre for Applied Clinical, Health and Care Research (CACHE) | |
| dc.contributor.institution | Department of Clinical, Pharmaceutical and Biological Science | |
| dc.description.status | Peer reviewed | |
| rioxxterms.type | Journal Article/Review | |
| herts.preservation.rarelyaccessed | true | |
