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dc.contributor.authorSinski, E.
dc.contributor.authorBairden, K.
dc.contributor.authorDuncan, J. L.
dc.contributor.authorEisler, M. C.
dc.contributor.authorHolmes, P. H.
dc.contributor.authorMcKellar, Quintin
dc.contributor.authorMurray, M.
dc.contributor.authorStear, M. J.
dc.date.accessioned2013-08-19T11:00:02Z
dc.date.available2013-08-19T11:00:02Z
dc.date.issued1995-09
dc.identifier.citationSinski , E , Bairden , K , Duncan , J L , Eisler , M C , Holmes , P H , McKellar , Q , Murray , M & Stear , M J 1995 , ' Local and plasma antibody responses to the parasitic larval stages of the abomasal nematode Ostertagia circumcincta ' , Veterinary Parasitology , vol. 59 , no. 2 , pp. 107-18 . https://doi.org/10.1016/0304-4017(94)00761-Z
dc.identifier.issn0304-4017
dc.identifier.otherPURE: 1431832
dc.identifier.otherPURE UUID: 61d1ffa0-fa07-4c4f-8579-d7161fea87a4
dc.identifier.otherPubMed: 7483234
dc.identifier.otherScopus: 0029095352
dc.identifier.urihttp://hdl.handle.net/2299/11365
dc.description.abstractOvine isotype-specific antibody responses to the parasitic larval stages of the abomasal nematode Ostertagia circumcincta were measured in a simple, indirect enzyme-linked immunosorbent assay. Analysis of variance of replicate tests showed that the assay was very reliable. There was substantial variation among individual sheep in their IgA and IgG1 responses even though the sheep had been matched for breed, age and sex, were born on the same farm, were reared identically and had the same history of exposure and challenge with O. circumcincta. The local IgA responses to a somatic extract of fourth-stage larvae were very similar to responses to excretory-secretory products of fourth-stage larvae. The responses to third stage larvae were correlated with the responses to fourth stage larvae. There was a negative correlation between parasite-specific plasma IgG1 and parasite-specific plasma IgA responses. There was only a moderate association between IgA responses in the mucus and the plasma. Therefore, antibody responses measured in plasma cannot be easily extrapolated to antibody responses in the abomasal mucus.en
dc.format.extent12
dc.language.isoeng
dc.relation.ispartofVeterinary Parasitology
dc.subjectSheep-Nematoda
dc.subjectOstertagia circumcincta
dc.subjectTeladorsagia circumcincta
dc.subjectImmunity-Nematoda
dc.titleLocal and plasma antibody responses to the parasitic larval stages of the abomasal nematode Ostertagia circumcinctaen
dc.contributor.institutionOffice of the Vice-Chancellor
dc.contributor.institutionVeterinary Science
dc.contributor.institutionGeography, Environment and Agriculture
dc.description.statusPeer reviewed
dcterms.dateAccepted1995-09
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.1016/0304-4017(94)00761-Z
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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