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dc.contributor.authorEleftherianos, Ioannis
dc.contributor.authorFoster, Stephen P.
dc.contributor.authorWilliamson, Martin S.
dc.contributor.authorDenholm, Ian
dc.date.accessioned2013-09-03T08:15:02Z
dc.date.available2013-09-03T08:15:02Z
dc.date.issued2008-10-23
dc.identifier.citationEleftherianos , I , Foster , S P , Williamson , M S & Denholm , I 2008 , ' Inheritance of L1014F and M918T sodium channel mutations associated with pyrethroid resistance in Myzus persicae ' , Biology Letters , vol. 4 , no. 5 , pp. 545-548 . https://doi.org/10.1098/rsbl.2008.0225
dc.identifier.issn1744-9561
dc.identifier.otherPURE: 1936623
dc.identifier.otherPURE UUID: 08f15d64-026b-4052-bfaa-037698235ae0
dc.identifier.otherWOS: 000259085900030
dc.identifier.otherScopus: 51549084470
dc.identifier.otherORCID: /0000-0001-9797-874X/work/35873712
dc.identifier.urihttp://hdl.handle.net/2299/11492
dc.description.abstractTwo amino acid substitutions (L1014F and M918T) in the voltage-gated sodium channel confer target-site resistance to pyrethroid insecticides in the peach potato aphid, Myzus persicae. Pyrethroid-resistant and -susceptible M. persicae clones with various combinations of these mutations were crossed under laboratory conditions, and the genotypes of aphid progeny were analysed by direct DNA sequencing of the IIS4-S6 region of the sodium channel gene. Segregation patterns showed that in aphids heterozygous for both L1014F and M918T, both mutations were present in the same resistance allele. Despite these mutations appearing largely recessive in other pest species, such aphids exhibited strong resistance to pyrethroids in leaf-dip bioassays. These results have important implications for the spread and management of pyrethroid resistance in field populations.en
dc.format.extent4
dc.language.isoeng
dc.relation.ispartofBiology Letters
dc.subjectKNOCKDOWN RESISTANCE
dc.subjectpyrethroids
dc.subjectdominance
dc.subjectPEACH-POTATO APHID
dc.subjectHEMIPTERA
dc.subjectknock-down resistance
dc.subjectsodium channel
dc.subjectMyzus persicae
dc.subjectinheritance
dc.subjectINSECTICIDE RESISTANCE
dc.titleInheritance of L1014F and M918T sodium channel mutations associated with pyrethroid resistance in Myzus persicaeen
dc.contributor.institutionDepartment of Human and Environmental Sciences
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionGeography, Environment and Agriculture
dc.contributor.institutionCrop Protection and Climate Change
dc.description.statusPeer reviewed
rioxxterms.versionofrecordhttps://doi.org/10.1098/rsbl.2008.0225
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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