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Dynein-dynactin complex subunits are differentially localized in brain and spinal cord, with selective involvement in pathological features of neurodegenerative disease

dc.contributor.authorAteh, D. D.
dc.contributor.authorHussain, I. K.
dc.contributor.authorMustafa, A. H.
dc.contributor.authorPrice, K. M.
dc.contributor.authorGulati, R.
dc.contributor.authorNickols, C. D.
dc.contributor.authorBird, M. M.
dc.contributor.authorGreensmith, L.
dc.contributor.authorHafezparast, M.
dc.contributor.authorFisher, E. M. C.
dc.contributor.authorBaker, C. S.
dc.contributor.authorMartin, J. E.
dc.date.accessioned2013-09-03T08:30:03Z
dc.date.available2013-09-03T08:30:03Z
dc.date.issued2008-02
dc.identifier.citationAteh , D D , Hussain , I K , Mustafa , A H , Price , K M , Gulati , R , Nickols , C D , Bird , M M , Greensmith , L , Hafezparast , M , Fisher , E M C , Baker , C S & Martin , J E 2008 , ' Dynein-dynactin complex subunits are differentially localized in brain and spinal cord, with selective involvement in pathological features of neurodegenerative disease ' , Neuropathology and Applied Neurobiology , vol. 34 , no. 1 , pp. 88-94 . https://doi.org/10.1111/j.1365-2990.2007.00924.x
dc.identifier.issn0305-1846
dc.identifier.otherPURE: 1995261
dc.identifier.otherPURE UUID: 822e14a9-d97e-44ca-8e89-db77eb472169
dc.identifier.otherPubMed: 18086204
dc.identifier.otherScopus: 38148998593
dc.identifier.urihttp://hdl.handle.net/2299/11497
dc.description.abstractThe dynein-dynactin complex, mostly recognized for axonal retrograde transport in neurones, has an ever growing list of essential subcellular functions. Here, the distribution of complex subunits in human central nervous system (CNS) has been assessed using immunohistochemistry in order to test the hypothesis that this may be altered in neurodegenerative disease.en
dc.format.extent7
dc.language.isoeng
dc.relation.ispartofNeuropathology and Applied Neurobiology
dc.subjectSpinal Cord
dc.subjectMicrotubule-Associated Proteins
dc.subjectNeurons
dc.subjectInclusion Bodies
dc.subjectHumans
dc.subjectBrain
dc.subjectNeurodegenerative Diseases
dc.subjectNeurofibrillary Tangles
dc.subjectImmunohistochemistry
dc.subjectDyneins
dc.subjectBiochemistry, Genetics and Molecular Biology(all)
dc.subjectNeuroscience(all)
dc.titleDynein-dynactin complex subunits are differentially localized in brain and spinal cord, with selective involvement in pathological features of neurodegenerative diseaseen
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionDepartment of Human and Environmental Sciences
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionAgriculture, Food and Veterinary Sciences
dc.contributor.institutionPharmacology and Clinical Science Research
dc.description.statusPeer reviewed
rioxxterms.versionofrecordhttps://doi.org/10.1111/j.1365-2990.2007.00924.x
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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