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dc.contributor.authorPuinean, Alin M.
dc.contributor.authorDenholm, Ian
dc.contributor.authorMillar, Neil S.
dc.contributor.authorNauen, Ralf
dc.contributor.authorWilliamson, Martin S.
dc.date.accessioned2013-09-05T07:30:11Z
dc.date.available2013-09-05T07:30:11Z
dc.date.issued2010-06
dc.identifier.citationPuinean , A M , Denholm , I , Millar , N S , Nauen , R & Williamson , M S 2010 , ' Characterisation of imidacloprid resistance mechanisms in the brown planthopper, Nilaparvata lugens Stal (Hemiptera: Delphacidae) ' , Pesticide Biochemistry and Physiology , vol. 97 , no. 2 , pp. 129-132 . https://doi.org/10.1016/j.pestbp.2009.06.008
dc.identifier.issn0048-3575
dc.identifier.otherPURE: 1936074
dc.identifier.otherPURE UUID: 71eff2f7-3a18-43c1-af4b-8cb5d4399c61
dc.identifier.otherWOS: 000279116800009
dc.identifier.otherScopus: 79953901316
dc.identifier.otherORCID: /0000-0001-9797-874X/work/35873698
dc.identifier.urihttp://hdl.handle.net/2299/11538
dc.description.abstractEffective control of the brown planthopper, Nilaparvata lugens Stal, across rice-growing regions of Asia has been seriously compromised over the last 2 years by the appearance of widespread resistance to the neonicotinoid insecticide, imidacloprid. Sequence analysis of the ligand-binding domain of the nicotinic acetylcholine receptor alpha 1 subunit from two field-collected resistant strains (CHN-2 and IND-11) did not reveal the Y151S point mutation previously implicated in conferring target-site resistance in this species. This result was supported by ligand-binding studies with [(3)H]-imidacloprid that showed no significant change in insecticide binding to isolated membranes from susceptible and resistant strains. In contrast, there was an approximate 5-fold increase in the mixed function oxidase activity for the two resistant strains suggesting that imidacloprid metabolism by increased cytochrome P450 monooxygenase activity is the major mechanism of resistance in these strains. Crown Copyright (C) 2009 Published by Elsevier Inc. All rights reserved.en
dc.format.extent4
dc.language.isoeng
dc.relation.ispartofPesticide Biochemistry and Physiology
dc.subjectImidacloprid
dc.subjectOxidase activity
dc.subjectPEACH-POTATO APHID
dc.subjectINSECTICIDES
dc.subjectMetabolic resistance
dc.subjectMYZUS-PERSICAE
dc.subjectNICOTINIC ACETYLCHOLINE-RECEPTORS
dc.subjectNEONICOTINOID CROSS-RESISTANCE
dc.subjectTETRANYCHUS-URTICAE ACARI
dc.subjectOVER-EXPRESSION
dc.subjectNeonicotinoid
dc.subjectNilaparvata lugens
dc.subjectBEMISIA-TABACI HEMIPTERA
dc.subjectALEYRODIDAE
dc.subjectSELECTIVITY
dc.titleCharacterisation of imidacloprid resistance mechanisms in the brown planthopper, Nilaparvata lugens Stal (Hemiptera: Delphacidae)en
dc.contributor.institutionDepartment of Human and Environmental Sciences
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionGeography, Environment and Agriculture
dc.contributor.institutionCrop and Environmental Protection
dc.contributor.institutionEcology
dc.contributor.institutionAgriculture, Veterinary and Food Sciences
dc.description.statusPeer reviewed
rioxxterms.versionofrecordhttps://doi.org/10.1016/j.pestbp.2009.06.008
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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