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Greater cognitive deterioration in women than men with Alzheimer's disease : a meta analysis

dc.contributor.authorIrvine, K.
dc.contributor.authorLaws, K.R.
dc.contributor.authorGale, T.M.
dc.contributor.authorKondel, T.K.
dc.date.accessioned2013-09-30T08:30:18Z
dc.date.available2013-09-30T08:30:18Z
dc.date.issued2012-11-01
dc.identifier.citationIrvine , K , Laws , K R , Gale , T M & Kondel , T K 2012 , ' Greater cognitive deterioration in women than men with Alzheimer's disease : a meta analysis ' , Journal of Clinical and Experimental Neuropsychology , vol. 34 , no. 9 , pp. 989-998 . https://doi.org/10.1080/13803395.2012.712676
dc.identifier.issn1380-3395
dc.identifier.otherORCID: /0000-0003-4087-3802/work/30907530
dc.identifier.otherORCID: /0000-0002-5065-0867/work/124446512
dc.identifier.urihttp://hdl.handle.net/2299/11671
dc.description.abstractStudies reporting on the cognitive abilities of men and women with Alzheimer's disease (AD) are surprisingly rare. We carried out a meta-analysis of neurocognitive data from 15 studies (n = 828 men; 1,238 women), which revealed a consistent male advantage on verbal and visuospatial tasks and tests of episodic and semantic memory. Moderator regression analyses showed that age, education level, and dementia severity did not significantly predict the male advantage. Reasons posited for this advantage include a reduction of estrogen in postmenopausal women, sex differences in AD pathology, and greater cognitive reserve in men.en
dc.format.extent10
dc.language.isoeng
dc.relation.ispartofJournal of Clinical and Experimental Neuropsychology
dc.subjectAPOLIPOPROTEIN-E
dc.subjectOLDER-ADULTS
dc.subjectAGE
dc.subjectGENDER-DIFFERENCES
dc.subjectAlzheimer's disease
dc.subjectVASCULAR DEMENTIA
dc.subjectVERBAL MEMORY
dc.subjectSEX-DIFFERENCES
dc.subjectSURGICALLY MENOPAUSAL WOMEN
dc.subjectSex differences
dc.subjectCognition
dc.subjectVisuospatial abilities
dc.subjectESTROGEN REPLACEMENT
dc.subjectVerbal abilities
dc.subjectREPLACEMENT THERAPY
dc.titleGreater cognitive deterioration in women than men with Alzheimer's disease : a meta analysisen
dc.contributor.institutionDepartment of Psychology
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionPsychology
dc.contributor.institutionCognitive Neuropsychology
dc.contributor.institutionScience & Technology Research Institute
dc.contributor.institutionHealth and Clinical Psychology Research Group
dc.contributor.institutionHealth Research Methods Unit
dc.contributor.institutionCentre for Research in Psychology and Sports
dc.contributor.institutionApplied Psychology Research Group
dc.contributor.institutionBasic and Clinical Science Unit
dc.contributor.institutionDepartment of Psychology, Sport and Geography
dc.contributor.institutionCentre for Health Services and Clinical Research
dc.contributor.institutionPsychology and NeuroDiversity Applied Research Unit
dc.description.statusPeer reviewed
dc.identifier.urlhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84868666775&partnerID=8YFLogxK
rioxxterms.versionofrecord10.1080/13803395.2012.712676
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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