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The genetic control of IgA activity against Teladorsagia circumcincta and its association with parasite resistance in naturally infected sheep

dc.contributor.authorStrain, S.A.J.
dc.contributor.authorBishop, S.C.
dc.contributor.authorHenderson, N.G.
dc.contributor.authorKerr, A.
dc.contributor.authorMcKellar, Quintin
dc.contributor.authorMitchell, S.
dc.contributor.authorStear, M.J.
dc.date.accessioned2013-10-01T15:00:14Z
dc.date.available2013-10-01T15:00:14Z
dc.date.issued2002-05
dc.identifier.citationStrain , S A J , Bishop , S C , Henderson , N G , Kerr , A , McKellar , Q , Mitchell , S & Stear , M J 2002 , ' The genetic control of IgA activity against Teladorsagia circumcincta and its association with parasite resistance in naturally infected sheep ' , Parasitology , vol. 124 , no. 05 , pp. 545-552 . https://doi.org/10.1017/S0031182002001531
dc.identifier.issn1469-8161
dc.identifier.otherPURE: 1409644
dc.identifier.otherPURE UUID: e4f5a596-b01f-4196-9be0-3b8a13883933
dc.identifier.otherBibtex: urn:fc2483447d41bb2de34a0b2307900372
dc.identifier.otherScopus: 0036092424
dc.identifier.urihttp://hdl.handle.net/2299/11706
dc.description.abstractPrevious studies in deliberately infected sheep have shown an association between IgA activity against 4th-stage larvae of Teladorsagia circumcincta and parasite growth, development and fecundity. The purpose of this research,,vas to determine if these results could be confirmed in naturally infected sheep and to explore the hypothesis that plasma IgA activity could help to identify resistant lambs with shorter adult nematodes. Plasma IgA activity was skewed with most animals having relatively low levels of IgA activity. Plasma IgA activity, was repeatable and highly heritable. Animals with increased IgA activity had lower egg counts and shorter adult female T. circumcincta. Therefore, under conditions of natural parasite challenge, plasma IgA activity, may help to identify lambs resistant to T. circumcincta.en
dc.format.extent8
dc.language.isoeng
dc.relation.ispartofParasitology
dc.subjectsheep
dc.subjectnematoda
dc.subjectTeladorsagia circumcincta
dc.subjectIgA
dc.subjectmarker
dc.subjectindicator trait
dc.titleThe genetic control of IgA activity against Teladorsagia circumcincta and its association with parasite resistance in naturally infected sheepen
dc.contributor.institutionOffice of the Vice-Chancellor
dc.contributor.institutionVeterinary Science
dc.contributor.institutionGeography, Environment and Agriculture
dc.description.statusPeer reviewed
rioxxterms.versionofrecordhttps://doi.org/10.1017/S0031182002001531
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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