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dc.contributor.authorRastogi, N.
dc.contributor.authorSmeeton, N.C.
dc.contributor.authorQureshi, S.A.
dc.identifier.citationRastogi , N , Smeeton , N C & Qureshi , S A 2009 , ' Factors related to successful transcatheter closure of atrial septal defects using the Amplatzer septal occluder ' , Pediatric Cardiology , vol. 30 , no. 7 , pp. 888-892 .
dc.identifier.otherPURE: 2358030
dc.identifier.otherPURE UUID: 8ec9e54c-f069-41f8-b1a5-8f8bdc41f5e4
dc.identifier.otherScopus: 75349083415
dc.identifier.otherORCID: /0000-0001-9460-5411/work/32622254
dc.description.abstractThe Amplatzer septal occluder (ASO) is used for transcatheter closure of atrial septal defects (ASDs). This study aimed to determine the factors influencing successful closure with the ASO. A retrospective analysis of 69 patients who underwent transcatheter ASD occlusion between 2003 and 2007 was performed. The ASO was successfully implanted during 67 (97%) of 69 procedures. A major adverse event occurred for 6 patients (9%), and 13 patients (19%) experienced a minor adverse event. The outcome for 53 cases (77%) was a composite clinical success. Patient age (p = 0.191) and consultant experience (p = 0.270) were not important factors in successful ASD occlusion. However, patient weight (p = 0.031), diameter of the defect (p = 0.030), device size (p = 0.044), aortic rim size (p = 0.002), and device/defect ratio (p <0.001) all were significant factors. Complications were significantly more likely for patients whose device/defect ratio was or = 1.333 (tight) (p <0.001). The device/defect ratio may provide a clinically useful tool with the potential to predict patients likely to experience an adverse event as a result of transcatheter ASD occlusion. A larger sample would enable refinement of the device/defect ratio and provide a more robust prediction of success.en
dc.relation.ispartofPediatric Cardiology
dc.titleFactors related to successful transcatheter closure of atrial septal defects using the Amplatzer septal occluderen
dc.contributor.institutionSchool of Health and Social Work
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionDepartment of Adult Nursing and Primary Care
dc.contributor.institutionCentre for Research in Public Health and Community Care
dc.description.statusPeer reviewed
dc.relation.schoolSchool of Health and Social Work
rioxxterms.typeJournal Article/Review

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