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dc.contributor.authorHofman, Michael S.
dc.contributor.authorSmeeton, N.C.
dc.contributor.authorRankin, Sheila C.
dc.contributor.authorNunan, Tom
dc.contributor.authorO'Doherty, Michael J.
dc.identifier.citationHofman , M S , Smeeton , N C , Rankin , S C , Nunan , T & O'Doherty , M J 2009 , ' Observer Variation in Interpreting 18F-FDG PET/CT Findings for Lymphoma Staging ' , Journal of Nuclear Medicine , vol. 50 , no. 10 , pp. 1594-1597 .
dc.identifier.otherPURE: 2358090
dc.identifier.otherPURE UUID: 2304eebf-2272-4065-af22-b9271c2d4a91
dc.identifier.otherScopus: 70349647607
dc.description.abstractMany studies demonstrate a high accuracy for PET in staging lymphoma, but few assess observer variation. This study quantified agreement for staging lymphoma with PET/CT. Methods: The PET/CT images of 100 patients with lymphoma who had been referred for staging were reviewed by 3 experienced observers, with 2 observers reviewing each series a second time. Ann Arbor stage and individual nodal and extranodal regions were assessed. Weighted κ (κw) and intraclass correlation coefficient were used to compare ratings. Results: Intra- and interobserver agreement was high for Ann Arbor stage (κw = 0.79–0.91), number of nodal regions involved (intraclass correlation coefficient, 0.83–0.93), and presence of extranodal disease (κ = 0.74–0.86). High agreement was also observed for all nodal regions (κw > 0.60) except hilar (κw = 0.56–0.82) and infraclavicular (κw = 0.14–0.55). Lower agreement was observed for bowel involvement (κw = 0.37–0.71). Conclusion: Experienced observers had a high level of agreement using PET/CT for lymphoma staging, supporting its use as a robust noninvasive staging tool. Further research is needed to evaluate observer variability for restaging during and after chemotherapy.en
dc.relation.ispartofJournal of Nuclear Medicine
dc.titleObserver Variation in Interpreting 18F-FDG PET/CT Findings for Lymphoma Stagingen
dc.contributor.institutionSchool of Health and Social Work
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionDepartment of Adult Nursing and Primary Care
dc.contributor.institutionCentre for Research in Public Health and Community Care
dc.description.statusPeer reviewed
dc.relation.schoolSchool of Health and Social Work
rioxxterms.typeJournal Article/Review

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