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dc.date.accessioned2013-11-07T00:14:05Z
dc.date.available2013-11-07T00:14:05Z
dc.date.issued2011-08-04
dc.identifier.citationReddy , T R K , Li , C , Fischer , P M & Dekker , L V 2011 , Patent: Preparation of pyrrole derivatives as S100 protein binding interaction inhibitors for the treatment of cancer and other diseases , Patent No. WO 2011/092505 A1 , IPC No. A61K31/4015 (2006.01) .
dc.identifier.otherPURE: 1410860
dc.identifier.otherPURE UUID: 5e48d6d0-27d1-47ea-938e-ad0dba8a3125
dc.identifier.urihttp://hdl.handle.net/2299/12090
dc.description.abstractThis invention relates to compounds that are inhibitors of S100 protein binding interactions, such as, for example, the annexin A2-S100A10 protein binding interaction. More specifically, this invention concerns certain substituted pyrrole derivatives of the general formula I or II as defined in patent, as well as processes for preparing these derivatives, pharmaceutical compositions comprising these derivatives and their use in the treatment, prevention or delay of progression of diseases in which S100 protein binding interactions are implicated (such as cancer).en
dc.language.isoeng
dc.subjectTRK Reddy
dc.subjectPyrrolidinones
dc.subject.classificationA61K31/4015 (2006.01)
dc.titlePatent: Preparation of pyrrole derivatives as S100 protein binding interaction inhibitors for the treatment of cancer and other diseasesen
dc.contributor.institutionDepartment of Pharmacy
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionMedicinal and Analytical Chemistry
dc.contributor.inventorReddy, Tummala Rama Krishna
dc.contributor.inventorLi, Chan
dc.contributor.inventorFischer, Peter M.
dc.contributor.inventorDekker, Lodewijk V.
dc.identifier.urlhttp://www.sumobrain.com/patents/wipo/S100-protein-binding-interaction-inhibitors/WO2011092505A1.pdf
dc.relation.schoolSchool of Life and Medical Sciences
dcterms.dateAccepted2011-08-04
rioxxterms.versionVoR
rioxxterms.typeOther
herts.preservation.rarelyaccessedtrue


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