dc.contributor.author | Zloh, Mire | |
dc.contributor.author | Gibbons, S. | |
dc.date.accessioned | 2014-01-08T16:30:37Z | |
dc.date.available | 2014-01-08T16:30:37Z | |
dc.date.issued | 2004-02-01 | |
dc.identifier.citation | Zloh , M & Gibbons , S 2004 , ' Molecular similarity of MDR inhibitors ' , International Journal of Molecular Sciences (IJMS) , vol. 5 , no. 2 , pp. 37-47 . https://doi.org/10.3390/i5020037 | |
dc.identifier.issn | 1661-6596 | |
dc.identifier.uri | http://hdl.handle.net/2299/12485 | |
dc.description | Everyone is free to re-use the published material if proper accreditation/citation of the original publication is given. http://creativecommons.org/licences/by/3.0/ | |
dc.description.abstract | The molecular similarity of multidrug resistance (MDR) inhibitors was evaluated using the point centred atom charge approach in an attempt to find some common features of structurally unrelated inhibitors. A series of inhibitors of bacterial MDR were studied and there is a high similarity between these in terms of their shape, presence and orientation of aromatic ring moieties. A comparison of the lipophilic properties of these molecules has also been conducted suggesting that this factor is important in MDR inhibition. | en |
dc.format.extent | 11 | |
dc.format.extent | 881932 | |
dc.language.iso | eng | |
dc.relation.ispartof | International Journal of Molecular Sciences (IJMS) | |
dc.title | Molecular similarity of MDR inhibitors | en |
dc.contributor.institution | Department of Pharmacy | |
dc.contributor.institution | Medicinal and Analytical Chemistry | |
dc.contributor.institution | School of Life and Medical Sciences | |
dc.contributor.institution | Health & Human Sciences Research Institute | |
dc.description.status | Peer reviewed | |
dc.identifier.url | http://www.scopus.com/inward/record.url?scp=2942609006&partnerID=8YFLogxK | |
rioxxterms.versionofrecord | 10.3390/i5020037 | |
rioxxterms.type | Journal Article/Review | |
herts.preservation.rarelyaccessed | true | |