| dc.contributor.author | Keating, Christopher | |
| dc.contributor.author | Holden-Dye, Lindy | |
| dc.contributor.author | Walker, Robert J. | |
| dc.date.accessioned | 2014-03-04T15:59:04Z | |
| dc.date.available | 2014-03-04T15:59:04Z | |
| dc.date.issued | 1996-03 | |
| dc.identifier.citation | Keating , C , Holden-Dye , L & Walker , R J 1996 , ' Investigation of the mode of action of nematode neuropeptides ' , Pesticide Science , vol. 46 , no. 3 , pp. 263-266 . https://doi.org/10.1002/(SICI)1096-9063(199603)46:3<263::AID-PS346>3.0.CO;2-U | |
| dc.identifier.issn | 0031-613X | |
| dc.identifier.uri | http://hdl.handle.net/2299/13003 | |
| dc.description.abstract | The neuropeptide AF2 has a complex set of actions on the dorsal muscle strip of Ascaris suum, including a potentiation of the acetylcholine-stimulated muscle contraction. Caffeine at 100 μm and 5 mm inhibited this potentiation, as did 100 μm theophylline in two out of six studies. The cyclic-AMP-potentiating compounds IBMX, dibutyryl cAMP and forskolin had no effect on the AF2-induced potentiation of the acetylcholine-stimulated muscle contraction. These preliminary data suggest that the potentiating action of AF2 is not mediated by a cAMP pathway | en |
| dc.language.iso | eng | |
| dc.relation.ispartof | Pesticide Science | |
| dc.title | Investigation of the mode of action of nematode neuropeptides | en |
| dc.contributor.institution | School of Life and Medical Sciences | |
| dc.contributor.institution | Centre for Research in Mechanisms of Disease and Drug Discovery | |
| dc.contributor.institution | Department of Clinical, Pharmaceutical and Biological Science | |
| dc.contributor.institution | Basic and Clinical Science Unit | |
| dc.contributor.institution | Centre for Health Services and Clinical Research | |
| dc.description.status | Peer reviewed | |
| rioxxterms.versionofrecord | 10.1002/(SICI)1096-9063(199603)46:3<263::AID-PS346>3.0.CO;2-U | |
| rioxxterms.type | Journal Article/Review | |
| herts.preservation.rarelyaccessed | true | |
