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The FMRFamide-like AF2 is present in the parasitic nematode Haemonchus contortus

dc.contributor.authorKeating, Christopher
dc.contributor.authorHolden-Dye, Lindy
dc.contributor.authorThorndyke, Michael C.
dc.contributor.authorWilliams, R.G.
dc.contributor.authorMallett, A.
dc.contributor.authorWalker, Robert J.
dc.date.accessioned2014-03-06T11:58:59Z
dc.date.available2014-03-06T11:58:59Z
dc.date.issued1995-11
dc.identifier.citationKeating , C , Holden-Dye , L , Thorndyke , M C , Williams , R G , Mallett , A & Walker , R J 1995 , ' The FMRFamide-like AF2 is present in the parasitic nematode Haemonchus contortus ' , Parasitology , vol. 111 , no. 4 , pp. 515-521 . https://doi.org/10.1017/S0031182000066026
dc.identifier.issn0031-1820
dc.identifier.urihttp://hdl.handle.net/2299/13032
dc.description.abstractPeptides belonging to the FMRFamide family are widely distributed amongst invertebrates. We report here on the isolation of the FMRFamide neuropeptide AF2 (Lys-His-Glu-Tyr-Leu-Arg-Phe-NH2) from the parasitic nematode Haemonchus contortus. Immunocytochemical techniques showed that FMRFamide-like material was distributed in several regions of these organisms including nerve cords and cell bodies of the central nervous system. AF2 was isolated using a method that employed 6 steps of reverse-phase HPLC. The concentration of AF2 in this organism was approximately 30 pmol/g of nematodeen
dc.language.isoeng
dc.relation.ispartofParasitology
dc.titleThe FMRFamide-like AF2 is present in the parasitic nematode Haemonchus contortusen
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionCentre for Research in Mechanisms of Disease and Drug Discovery
dc.contributor.institutionDepartment of Clinical, Pharmaceutical and Biological Science
dc.contributor.institutionBasic and Clinical Science Unit
dc.contributor.institutionCentre for Health Services and Clinical Research
dc.description.statusPeer reviewed
rioxxterms.versionofrecord10.1017/S0031182000066026
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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