dc.contributor.author | Forbes, Ian T. | |
dc.contributor.author | Cooper, David G. | |
dc.contributor.author | Dodds, Emma K. | |
dc.contributor.author | Hickey, Deirdre M. B. | |
dc.contributor.author | Ife, Robert J. | |
dc.contributor.author | Meeson, Malcolm | |
dc.contributor.author | Stockley, Martin | |
dc.contributor.author | Berkhout, Theo | |
dc.contributor.author | Gohil, Jayneeta | |
dc.contributor.author | Groot, Pieter H. E. | |
dc.contributor.author | Moores, Kitty E. | |
dc.date.accessioned | 2014-06-11T11:30:36Z | |
dc.date.available | 2014-06-11T11:30:36Z | |
dc.date.issued | 2000-08-21 | |
dc.identifier.citation | Forbes , I T , Cooper , D G , Dodds , E K , Hickey , D M B , Ife , R J , Meeson , M , Stockley , M , Berkhout , T , Gohil , J , Groot , P H E & Moores , K E 2000 , ' CCR2B receptor antagonists : Conversion of a weak HTS hit to a potent lead compound ' , Bioorganic and Medicinal Chemistry Letters , vol. 10 , no. 16 , pp. 1803-1806 . https://doi.org/10.1016/S0960-894X(00)00347-4 | |
dc.identifier.issn | 0960-894X | |
dc.identifier.other | PURE: 7129741 | |
dc.identifier.other | PURE UUID: 84bfec09-b8f6-42bc-8d0d-3530c017eb54 | |
dc.identifier.other | Scopus: 0034698896 | |
dc.identifier.other | PubMed: 10969972 | |
dc.identifier.uri | http://hdl.handle.net/2299/13701 | |
dc.description.abstract | A weak HTS hit at the CCR2B receptor has been converted into a potent antagonist by array SAR studies. Selectivity over the closely related CCR5 receptor is also achieved. (C) 2000 Elsevier Science Ltd. All rights reserved. | en |
dc.format.extent | 4 | |
dc.language.iso | eng | |
dc.relation.ispartof | Bioorganic and Medicinal Chemistry Letters | |
dc.subject | Biochemistry | |
dc.subject | Molecular Biology | |
dc.subject | Organic Chemistry | |
dc.subject | Drug Discovery | |
dc.subject | Pharmaceutical Science | |
dc.title | CCR2B receptor antagonists : Conversion of a weak HTS hit to a potent lead compound | en |
dc.contributor.institution | School of Life and Medical Sciences | |
dc.contributor.institution | Department of Pharmacy | |
dc.contributor.institution | Health & Human Sciences Research Institute | |
dc.contributor.institution | Medicinal and Analytical Chemistry | |
dc.description.status | Peer reviewed | |
rioxxterms.versionofrecord | https://doi.org/10.1016/S0960-894X(00)00347-4 | |
rioxxterms.type | Journal Article/Review | |
herts.preservation.rarelyaccessed | true | |