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        25C-NBOMe: preliminary data on pharmacology, psychoactive effects and toxicity of a new potent hallucinogenic drug

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        Author
        Bersani, Francesco Saverio
        Corazza, Ornella
        Albano, Gabriella
        Valeriani, Giuseppe
        Santacroce, Rita
        Bolzan, Flamina
        Cinosi, Eduardo
        Simonato, Pierluigi
        Martinotti, Giovanni
        Bersani, Giuseppe
        Schifano, Fabrizio
        Attention
        2299/13953
        Abstract
        Introduction. The use of novel psychoactive substances (NPSs) has rapidly increased as well as their online availability. The aim of this paper is to provide a comprehensive review of the nature and the risks associated with 25C-NBOMe, which has recently appeared in the drug market. Methods. A systematic analysis of the scientific literature and a qualitative assessment of online and media resources (e.g., e-newsgroups, chat-rooms, and e-newsletters) in 10 languages were carried out. Results. 25C-NBOMe is sold online as legal LSD or as research chemical with different designations such as “Boom,” “Pandora,” “Holland film,” or “N-bomb.” It is a partial agonist of 5-HT2A receptors. It is usually ingested orally/sublingually and, less commonly, nasally, through injection, vaginally, rectally, and smoked. Its effects include sublingual numbing, stimulation, “body high,” hallucinations, dissociation, and anxiety. 25C-NBOMe presents high risk of overdoses; acute toxicity and fatalities have been reported. Conclusions. 25C-NBOMe consumption represents an emerging phenomenon with potential harmful effects. Its use is increased by its online availability at low costs. Health and other professionals should be informed about this new trend of substance use
        Publication date
        2014-07-03
        Published in
        BioMed Research International
        Published version
        https://doi.org/10.1155/2014/734749
        Other links
        http://hdl.handle.net/2299/13953
        Relations
        School of Life and Medical Sciences
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