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dc.contributor.authorSpecka, Michael
dc.contributor.authorÖning, Antje
dc.contributor.authorKluwig, Jürgen
dc.contributor.authorSchifano, Fabrizio
dc.contributor.authorBanger, Markus
dc.contributor.authorLange, Wolfgang
dc.contributor.authorLax, Hildegard
dc.contributor.authorMarrziniak, Bärbel
dc.contributor.authorSchüngel, Claudia
dc.contributor.authorScherbaum, Norbert
dc.date.accessioned2014-11-06T11:29:25Z
dc.date.available2014-11-06T11:29:25Z
dc.date.issued2013-12-01
dc.identifier.citationSpecka , M , Öning , A , Kluwig , J , Schifano , F , Banger , M , Lange , W , Lax , H , Marrziniak , B , Schüngel , C & Scherbaum , N 2013 , ' Can reinforcement-based interventions to reduce drug use successfully be adapted to routine opioid maintenance treatment? ' , Annali dell'Istituto Superiore di Sanita , vol. 49 , no. 4 , pp. 358-364 . https://doi.org/10.4415/ANN-13-04-07
dc.identifier.issn0021-2571
dc.identifier.otherPURE: 7723477
dc.identifier.otherPURE UUID: ecda660f-def5-4453-b9a8-58fbbc657fa7
dc.identifier.otherScopus: 84892418033
dc.identifier.urihttp://hdl.handle.net/2299/14696
dc.description.abstractIntroduction. Comorbid substance related disorders are a major health problem for patients in opioid maintenance treatment (OMT). It was investigated whether a reinforcement scheme adapted to the regulatory and financial restrictions of routine treatment reduces concomitant drug use.Methods. OMT patients from 7 clinics who were using cocaine, benzodiazepines, heroin or amphetamines were randomly allocated to either treatment as usual (n = 64) or treatment with an additional escalating reinforcement scheme (n = 72) in which a patient's number of weekly take-home dosages was increased after 1, 4, 8 and 12 consecutive weeks with drug-free urine specimens. Trial duration was 26 weeks. Results. Completion rates were 64% for controls and 62.5% in the experimental group. Mean number of drug-free weeks was 11.3 (SD 8.5) for the control group and 9.8 (8.9) for the experimental group (p = 0.30). Conclusion. The intervention was not effective compared to routine treatment. Additional features might be necessary to achieve an effect, e.g. a higher frequency of urine sampling or use of other reinforcers. It has to be further investigated how interventions which have been proven effective in experimental studies can successfully be adapted to routine care conditions.en
dc.format.extent7
dc.language.isoeng
dc.relation.ispartofAnnali dell'Istituto Superiore di Sanita
dc.subjectConcomitant drug use
dc.subjectOpiate dependence
dc.subjectOpioid maintenance treatment
dc.subjectReinforcement
dc.subjectPublic Health, Environmental and Occupational Health
dc.titleCan reinforcement-based interventions to reduce drug use successfully be adapted to routine opioid maintenance treatment?en
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionCentre for Clinical Practice, Safe Medicines and Drug Misuse Research
dc.contributor.institutionPatient and Medicines Safety
dc.contributor.institutionPrescription and Illicit Drug Misuse
dc.description.statusPeer reviewed
dc.relation.schoolSchool of Life and Medical Sciences
dcterms.dateAccepted2013-12-01
rioxxterms.versionofrecordhttps://doi.org/10.4415/ANN-13-04-07
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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