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        Oral Delivery of Hydrophilic Drugs to the Brain

        Author
        Centre for Research into Topical Drug Delivery and Toxicology
        Nanopharmaceutics
        Pharmaceutics
        Department of Pharmacy
        School of Life and Medical Sciences
        Health & Human Sciences Research Institute
        Lalatsa, Aikaterini
        Attention
        2299/15242
        Abstract
        A composition comprising a lipophilic derivative of a hydrophilic drug and an amphiphile compound for use in therapy wherein the composition is orally administered to the human or animal body. The invention includes derivatives such as palmitoylated Leucine[5]-Enkephalin and is useful in the treatment of schizophrenia, obsesity, pain and sleep disorders, psychiatric diseases, neurodegenerative conditions, brain cancers and infective diseases.
        Publication date
        2010-09-10
        Other links
        http://hdl.handle.net/2299/15242
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