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dc.contributor.authorHutter, Victoria
dc.contributor.authorHilgendorf, Constanze
dc.contributor.authorBrown, Alan
dc.contributor.authorCooper, Anne
dc.contributor.authorZann, Vanessa
dc.contributor.authorPritchard, David
dc.contributor.authorBosquillon, Cynthia
dc.identifier.citationHutter , V , Hilgendorf , C , Brown , A , Cooper , A , Zann , V , Pritchard , D & Bosquillon , C 2010 , ' Characterisation of ATP-binding cassette (ABC) transporters in the Calu-3 human bronchial epithelial cell culture model ' , Journal of Pharmacy and Pharmacology , vol. 62 , no. 10 , pp. 1225-1226 .
dc.identifier.otherPURE: 7983713
dc.identifier.otherPURE UUID: e16c870a-dfce-4468-97af-fe9bb192c289
dc.description.abstractExpression and functionality of ATP-binding cassette (ABC) transporters were assessed in Calu-3 cell monolayers cultured at an air-liquid interface. Transporter gene expression was in agreement with published data in human lungs with the exception of BSEP which was over-expressed in Calu-3 cells. Net secretory transport of the ABC substrate 3H-digoxin was reduced in presence of the inhibitors verapamil, PSC833 and MK571. However, the transporter(s) involved could not be identified.en
dc.relation.ispartofJournal of Pharmacy and Pharmacology
dc.titleCharacterisation of ATP-binding cassette (ABC) transporters in the Calu-3 human bronchial epithelial cell culture modelen
dc.contributor.institutionDepartment of Pharmacy
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionCentre for Research into Topical Drug Delivery and Toxicology
dc.contributor.institutionAirway Group
dc.description.statusPeer reviewed
dc.relation.schoolSchool of Life and Medical Sciences

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