Show simple item record

dc.contributor.authorHutter, Victoria
dc.contributor.authorHilgendorf, Constanze
dc.contributor.authorBrown, Alan
dc.contributor.authorCooper, Anne
dc.contributor.authorZann, Vanessa
dc.contributor.authorPritchard, David
dc.contributor.authorBosquillon, Cynthia
dc.date.accessioned2015-01-19T14:32:43Z
dc.date.available2015-01-19T14:32:43Z
dc.date.issued2010-10
dc.identifier.citationHutter , V , Hilgendorf , C , Brown , A , Cooper , A , Zann , V , Pritchard , D & Bosquillon , C 2010 , ' Characterisation of ATP-binding cassette (ABC) transporters in the Calu-3 human bronchial epithelial cell culture model ' , Journal of Pharmacy and Pharmacology , vol. 62 , no. 10 , pp. 1225-1226 .
dc.identifier.issn0022-3573
dc.identifier.otherPURE: 7983713
dc.identifier.otherPURE UUID: e16c870a-dfce-4468-97af-fe9bb192c289
dc.identifier.urihttp://hdl.handle.net/2299/15245
dc.description.abstractExpression and functionality of ATP-binding cassette (ABC) transporters were assessed in Calu-3 cell monolayers cultured at an air-liquid interface. Transporter gene expression was in agreement with published data in human lungs with the exception of BSEP which was over-expressed in Calu-3 cells. Net secretory transport of the ABC substrate 3H-digoxin was reduced in presence of the inhibitors verapamil, PSC833 and MK571. However, the transporter(s) involved could not be identified.en
dc.format.extent1
dc.language.isoeng
dc.relation.ispartofJournal of Pharmacy and Pharmacology
dc.titleCharacterisation of ATP-binding cassette (ABC) transporters in the Calu-3 human bronchial epithelial cell culture modelen
dc.contributor.institutionDepartment of Pharmacy
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionCentre for Research into Topical Drug Delivery and Toxicology
dc.contributor.institutionAirway Group
dc.contributor.institutionPharmaceutics
dc.description.statusPeer reviewed
dc.relation.schoolSchool of Life and Medical Sciences
dcterms.dateAccepted2010-10
rioxxterms.typeOther
herts.preservation.rarelyaccessedtrue


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record