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dc.contributor.authorWithers, Caroline A.
dc.contributor.authorCook, Michael T.
dc.contributor.authorMethven, Lisa
dc.contributor.authorGosney, Margot A.
dc.contributor.authorKhutoryanskiy, Vitaliy V.
dc.date.accessioned2015-06-01T14:21:04Z
dc.date.available2015-06-01T14:21:04Z
dc.date.issued2013-11-01
dc.identifier.citationWithers , C A , Cook , M T , Methven , L , Gosney , M A & Khutoryanskiy , V V 2013 , ' Investigation of milk proteins binding to the oral mucosa ' , Food and Function , vol. 4 , no. 11 , pp. 1668-1674 . https://doi.org/10.1039/c3fo60291e
dc.identifier.issn2042-6496
dc.identifier.otherPURE: 8599408
dc.identifier.otherPURE UUID: 3de3de83-6461-4cea-b527-f8511a771e19
dc.identifier.otherScopus: 84886709178
dc.identifier.otherPubMed: 24092277
dc.identifier.urihttp://hdl.handle.net/2299/15973
dc.descriptionThis article is licensed under a Creative Commons Attribution 3.0 Unported Licence
dc.description.abstractHigh protein dairy beverages are considered to be mouth drying. The drying sensation may be due to the product protein content; however the mechanism of this mouth drying is uncertain. This study investigated the potential adhesion of milk proteins to porcine oral mucosa in vitro. Purified casein and β-lactoglobulin were fluorescently labelled, placed on porcine oral mucosal tissues and their resistance to wash out with simulated saliva was monitored using fluorescence microscopy. Casein was found to be more adhesive to porcine mucosa than β-lactoglobulin. Some investigation into the reason for this difference in mucoadhesion was conducted by thiol-content analysis, rheology and zeta-potential measurements. The higher viscosity of casein solution and smaller zeta-potential is believed to be responsible for its better retention on mucosal surfaces. These findings suggest that casein and whey protein are both capable of binding and eliciting mouth drying in high protein dairy beverages.en
dc.format.extent7
dc.language.isoeng
dc.relation.ispartofFood and Function
dc.subjectFood Science
dc.subjectMedicine(all)
dc.titleInvestigation of milk proteins binding to the oral mucosaen
dc.contributor.institutionCentre for Research into Topical Drug Delivery and Toxicology
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionDepartment of Pharmacy
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.description.statusPeer reviewed
rioxxterms.versionVoR
rioxxterms.versionofrecordhttps://doi.org/10.1039/c3fo60291e
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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