| dc.contributor.author | Dimairo, Munya | |
| dc.contributor.author | Boote, Jonathan | |
| dc.contributor.author | Julious, Steven A. | |
| dc.contributor.author | Nicholl, Jon | |
| dc.contributor.author | Todd, Susan | |
| dc.date.accessioned | 2015-10-07T09:28:48Z | |
| dc.date.available | 2015-10-07T09:28:48Z | |
| dc.date.issued | 2015-09-28 | |
| dc.identifier.citation | Dimairo , M , Boote , J , Julious , S A , Nicholl , J & Todd , S 2015 , ' Missing steps in a staircase : a qualitative study of the perspectives of key stakeholders on the use of adaptive designs in confirmatory trials ' , Trials , vol. 16 , 430 . https://doi.org/10.1186/s13063-015-0958-9 | |
| dc.identifier.issn | 1745-6215 | |
| dc.identifier.uri | http://hdl.handle.net/2299/16500 | |
| dc.description | Date of Acceptance: 14/09/2015. © 2015 Dimairo et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated | |
| dc.description.abstract | Despite the promising benefits of adaptive designs (ADs), their routine use, especially in confirmatory trials, is lagging behind the prominence given to them in the statistical literature. Much of the previous research to understand barriers and potential facilitators to the use of ADs has been driven from a pharmaceutical drug development perspective, with little focus on trials in the public sector. In this paper, we explore key stakeholders’ experiences, perceptions and views on barriers and facilitators to the use of ADs in publicly funded confirmatory trials | en |
| dc.format.extent | 16 | |
| dc.format.extent | 648550 | |
| dc.language.iso | eng | |
| dc.relation.ispartof | Trials | |
| dc.title | Missing steps in a staircase : a qualitative study of the perspectives of key stakeholders on the use of adaptive designs in confirmatory trials | en |
| dc.contributor.institution | School of Health and Social Work | |
| dc.contributor.institution | Department of Adult Nursing and Primary Care | |
| dc.contributor.institution | Health & Human Sciences Research Institute | |
| dc.contributor.institution | Centre for Research in Public Health and Community Care | |
| dc.description.status | Peer reviewed | |
| rioxxterms.versionofrecord | 10.1186/s13063-015-0958-9 | |
| rioxxterms.type | Journal Article/Review | |
| herts.preservation.rarelyaccessed | true | |
