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dc.contributor.authorCook, Michael T.
dc.contributor.authorKhutoryanskiy, Vitaliy V.
dc.date.accessioned2016-03-30T14:12:00Z
dc.date.available2016-03-30T14:12:00Z
dc.date.issued2015-11-30
dc.identifier.citationCook , M T & Khutoryanskiy , V V 2015 , ' Mucoadhesion and mucosa-mimetic materials - a mini-review ' , International Journal of Pharmaceutics , vol. 495 , no. 2 , pp. 991-998 . https://doi.org/10.1016/j.ijpharm.2015.09.064
dc.identifier.issn0378-5173
dc.identifier.otherPURE: 9274121
dc.identifier.otherPURE UUID: b7cdfac2-610c-4c1e-975b-14cf29d4094c
dc.identifier.otherPubMed: 26440734
dc.identifier.otherScopus: 84944145057
dc.identifier.urihttp://hdl.handle.net/2299/16856
dc.description.abstractMucoadhesion describes an attractive interaction between dosage form and mucosal membrane. The evaluation of mucoadhesive excipients often requires the use of ex vivo mucosal tissues taken from laboratory animals. These can be difficult to source, highly heterogeneous, and require the use of animal products. Thus, from both a user-convenience and ethical point-of-view, it is desirable to produce a synthetic alternative to these tissues - a mucosa-mimetic material. In this mini-review, the use of alternative materials to test the performance of mucoadhesives is reviewed and discussed. There is a surprising prevalence of the use of mucosa-mimics in the literature, which hitherto has not been compiled and compared.en
dc.language.isoeng
dc.relation.ispartofInternational Journal of Pharmaceutics
dc.titleMucoadhesion and mucosa-mimetic materials - a mini-reviewen
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionHealth & Human Sciences Research Institute
dc.contributor.institutionDepartment of Pharmacy
dc.contributor.institutionDepartment of Pharmacy, Pharmacology and Postgraduate Medicine
dc.contributor.institutionCentre for Research into Topical Drug Delivery and Toxicology
dc.description.statusPeer reviewed
dc.date.embargoedUntil2016-10-04
rioxxterms.versionAM
rioxxterms.versionofrecordhttps://doi.org/10.1016/j.ijpharm.2015.09.064
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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