Show simple item record

dc.contributor.authorSmith, Allan
dc.contributor.authorBoursnell, M. E. G.
dc.contributor.authorBinns, M. M.
dc.contributor.authorBrown, T. D. K.
dc.contributor.authorInglis, S. C.
dc.contributor.editorLai, Michael M.C.
dc.date.accessioned2016-04-07T11:41:27Z
dc.date.available2016-04-07T11:41:27Z
dc.date.issued1987
dc.identifier.citationSmith , A , Boursnell , M E G , Binns , M M , Brown , T D K & Inglis , S C 1987 , Identification of a new gene product encoded by mRNA D of Infectious Bronchitis Virus. in M M C Lai (ed.) , Coronaviruses . Advances in Experimental Medicine and Biology , vol. 218 , Springer , pp. 47-54 . https://doi.org/10.1007/978-1-4684-1280-2_6
dc.identifier.isbn978-1-4684-1282-6
dc.identifier.isbn978-1-4684-1280-2
dc.identifier.issn0065-2598
dc.identifier.otherPURE: 9791644
dc.identifier.otherPURE UUID: 63bbcaad-d02f-4bce-a06c-d5c541724f3c
dc.identifier.otherScopus: 0023477869
dc.identifier.urihttp://hdl.handle.net/2299/17078
dc.description.abstractThe coronavirus Infectious Bronchitis Virus (IBV), a pathogen of chickens, has a genome structure typical of a coronavirus. The virus particle contains a single-stranded RNA molecule of approximately 27kb with positive polarity, and in infected cells six species of virus-specific mRNA are produced, designated RNA A to RNA F in order of increasing size (RNA F corresponding to the size of the genomic RNA). These RNAs form a nested set, in which the sequences in each of the subgenomic RNAs are also represented in all the larger RNAs; these RNA species each have a short ‘leader’ sequence corresponding to the 5′ end of the genomic RNA followed by progressively larger amounts of information derived from its 3′ -end. For each mRNA, the region of sequence which is not contained in the next smallest RNA is assumed to be used for translation of viral proteins. Polypeptide products have been assigned for RNAs A, C and E (nucleoprotein, membrane protein and the spike protein precursor respectively), but the coding function of the other RNAs has not so far been established, although it has generally been assumed that RNA F codes for the viral RNA-dependent-RNA-polymerase.en
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofCoronaviruses
dc.relation.ispartofseriesAdvances in Experimental Medicine and Biology
dc.titleIdentification of a new gene product encoded by mRNA D of Infectious Bronchitis Virus.en
dc.contributor.institutionSchool of Humanities
dc.description.statusPeer reviewed
dc.relation.schoolSchool of Humanities
dcterms.dateAccepted1987
rioxxterms.versionofrecordhttps://doi.org/10.1007/978-1-4684-1280-2_6
rioxxterms.typeOther
herts.preservation.rarelyaccessedtrue


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record