In vitro and in vivo TNFa synthesis modulation by methylguanidine, an uremic catabolyte
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Author
Autore, G.
Marzocco, S.
Sorrentino, R.
Mirone, V. G.
Baydoun, A. R.
Pinto, A.
Attention
2299/1708
Abstract
We have investigated whether methylguanidine (MG), an uremic toxin, modulates the expression of the inducible nitric oxide synthase (iNOS) and nitric oxide (NO) release in vitro in LPS-induced J774 macrophages.