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Synthesis and Spectral Characterization of Benzo[6,7] [1,5]diazocino[2,1-a]isoindol-12-(14H)-one Derivatives

dc.contributor.authorBassin, Jatinder
dc.contributor.authorAnagani, Bhavani
dc.contributor.authorBenham, Christopher
dc.contributor.authorGoyal, Madhu
dc.contributor.authorHashemian , Maryam
dc.contributor.authorGerhard, Ute
dc.date.accessioned2016-10-18T16:12:27Z
dc.date.available2016-10-18T16:12:27Z
dc.date.issued2016-07-23
dc.identifier.citationBassin , J , Anagani , B , Benham , C , Goyal , M , Hashemian , M & Gerhard , U 2016 , ' Synthesis and Spectral Characterization of Benzo[6,7] [1,5]diazocino[2,1-a]isoindol-12-(14H)-one Derivatives ' , Molecules , vol. 21 , no. 8 , pp. 967-979 . https://doi.org/10.3390/molecules21080967
dc.identifier.urihttp://hdl.handle.net/2299/17268
dc.description© 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
dc.description.abstractA simple synthetic route to benzo[6,7][1,5]diazocino[2,1-a]isoindol-12(14H)-one ring system is developed from readily available starting materials 3-(2-oxo-2-phenylethyl) isobenzofuran-1(3H)-ones and 2-(aminomethyl)aniline catalysed by para-toluenesulfonic acid in toluene in 27-85% yields. The 1H- and 13C-NMR spectra of the final products were assigned using a variety of one and two-dimensional NMR experiments. The distinction between the two potential isomers of the final products was made on the basis of heteronuclear multiple bond connectivity NMR spectra (HMBC).en
dc.format.extent13
dc.format.extent306967
dc.language.isoeng
dc.relation.ispartofMolecules
dc.titleSynthesis and Spectral Characterization of Benzo[6,7] [1,5]diazocino[2,1-a]isoindol-12-(14H)-one Derivativesen
dc.contributor.institutionVeterinary Science
dc.contributor.institutionMicrobiology and Biotechnology
dc.contributor.institutionSchool of Life and Medical Sciences
dc.contributor.institutionTRP Ion channels
dc.contributor.institutionBasic and Clinical Science Unit
dc.contributor.institutionBiosciences Research Group
dc.contributor.institutionCentre for Health Services and Clinical Research
dc.contributor.institutionPsychopharmacology, Drug Misuse and Novel Psychoactive Substances Unit
dc.contributor.institutionCentre for Research in Mechanisms of Disease and Drug Discovery
dc.contributor.institutionDepartment of Clinical, Pharmaceutical and Biological Science
dc.contributor.institutionCentre for Future Societies Research
dc.description.statusPeer reviewed
rioxxterms.versionofrecord10.3390/molecules21080967
rioxxterms.typeJournal Article/Review
herts.preservation.rarelyaccessedtrue


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